| ACKNOWLEDGEMENTS | 第7-13页 |
| abstract | 第13-15页 |
| CHAPTER 1 LITERATURE REVIEW | 第16-60页 |
| 1.1 Background Information | 第16-17页 |
| 1.2 Food safety hazard components | 第17-28页 |
| 1.2.1 Biological hazards | 第18-25页 |
| 1.2.2 Chemical hazards | 第25-28页 |
| 1.2.3 Physical hazards | 第28页 |
| 1.3 Research Direction | 第28-29页 |
| 1.4 Research Objectives | 第29页 |
| 1.5 The introduction of molecularly-imprinted polymers | 第29-31页 |
| 1.6 Synthesis of MIPs | 第31-45页 |
| 1.6.1 Covalent, non-covalent and semi-covalent approaches | 第34-36页 |
| 1.6.2 Synthesis protocols | 第36-45页 |
| 1.7 Template removal | 第45-48页 |
| 1.7.1 Solvent extraction | 第45-46页 |
| 1.7.2 Physically-assisted extraction | 第46-47页 |
| 1.7.3 Subcritical or Supercritical solvent extraction | 第47-48页 |
| 1.8 Applications of molecularly-imprinted polymers | 第48-59页 |
| 1.8.1 Molecularly-imprinted solid-phase extraction (MISPE) | 第49-51页 |
| 1.8.2 Molecularly-imprinted polymers as chemical sensors and biosensors | 第51-53页 |
| 1.8.3 Molecularly-imprinted polymers as catalytic materials | 第53-55页 |
| 1.8.4 Molecularly-imprinted polymers as drug delivery | 第55-59页 |
| 1.9 Conclusion | 第59-60页 |
| CHAPTER 2 EXPLOITING ALLYL-β-CYCLODEXTRIN AS FUNCTIONALMONOMERS IN MOLECULAR IMPRINTING FOR SELECTIVERECOGNITION OF PHTHALATES | 第60-84页 |
| 2.1 Introduction | 第60-62页 |
| 2.2 Experimental Section | 第62-68页 |
| 2.2.1 Chemicals | 第62-63页 |
| 2.2.2 Instruments | 第63页 |
| 2.2.3 The preparation of allyl-β-CD interaction | 第63-64页 |
| 2.2.4 The synthetic polymerization of MIPs | 第64页 |
| 2.2.5 Binding assays | 第64-68页 |
| 2.2.5.1 The influence of solvent on binding factor | 第64-65页 |
| 2.2.5.2. The binding specificity | 第65-66页 |
| 2.2.5.3. Binding dynamics and competitiveness | 第66页 |
| 2.2.5.4 Preparation of Molecularly Imprinted Solid-Phase Extraction (MISPE) Procedure | 第66-68页 |
| 2.3 Results and Discussion | 第68-82页 |
| 2.3.1 Characterization of the synthesized MIPs | 第68-72页 |
| 2.3.2 Binding assays | 第72-82页 |
| 3.3.2.1 The influence of solvent on binding factor | 第72-73页 |
| 2.3.2.2 The binding specificity | 第73-76页 |
| 2.3.2.3 Binding dynamics and competitiveness | 第76-78页 |
| 2.3.2.4 MISPE procedure | 第78-82页 |
| 2.4 Conclusion | 第82-84页 |
| CHAPTER 3 USING MOLECULARLY-IMPRINTED POLYMERS AS THEEXTRACTED SORBENTS OF CLENBUTEROL AHEAD OF LIQUIDCHROMATOGRAPHIC DETERMINATION | 第84-103页 |
| 3.1 Introduction | 第84-86页 |
| 3.2 Experimental Section | 第86-92页 |
| 3.2.1 Chemicals | 第86-87页 |
| 3.2.2 Instruments | 第87页 |
| 3.2.3 The preparation of allyl-β-CD interaction | 第87-88页 |
| 3.2.4 The synthetic polymerization of MIPs | 第88-89页 |
| 3.2.5 Binding assays | 第89-92页 |
| 3.2.5.1 The influence of adsorption solvent on the binding factor | 第89页 |
| 3.2.5.2 The binding specificity | 第89-90页 |
| 3.2.5.3 Binding dynamics and competitiveness | 第90页 |
| 3.2.5.4 Procedure for preparation of Molecularly Imprinted Solid-Phase Extraction (MISPE) | 第90-92页 |
| 3.3 Results and Discussion | 第92-102页 |
| 3.3.1 Characterization of the synthesized MIPs | 第92-95页 |
| 3.3.2 Binding assays | 第95-102页 |
| 3.3.2.1 The influence of adsorption solvent on the binding factor | 第95-97页 |
| 3.3.2.3 Binding dynamics and competitiveness | 第97-99页 |
| 3.3.2.4 Validation of method via MISPE procedure | 第99-102页 |
| 3.3.2.5 Real sample analysis | 第102页 |
| 3.4 Conclusion | 第102-103页 |
| CHAPTER 4 SYNTHESIS AND APPLICATION OF SELECTIVE ADSORBENTFOR PIRIMICARB PESTICIDE IN AQUEOUS MEDIA USING ALLYL-β-CYCLODEXTRIN AND METHACRYLIC ACID FUNCTIONAL MONOMERS | 第103-122页 |
| 4.1 Introduction | 第103-105页 |
| 4.2 Experimental Section | 第105-109页 |
| 4.2.1 Chemicals | 第105-106页 |
| 4.2.2 Instruments | 第106页 |
| 4.2.3 The preparation of allyl-β-CD interaction | 第106页 |
| 4.2.4 The synthetic polymerization of MIPs | 第106-107页 |
| 4.2.5 The influence of adsorption solvent on binding factor | 第107页 |
| 4.2.6 The binding specificity | 第107-108页 |
| 4.2.7 Preparation for Molecularly Imprinted Solid Phase Extraction(MISPE) procedure | 第108-109页 |
| 4.3 Results and Discussion | 第109-120页 |
| 4.3.1 Characterization of the synthesized MIPs | 第109-111页 |
| 4.3.2 Adsorption solvent evaluation | 第111-113页 |
| 4.3.3 The binding specificity | 第113-114页 |
| 4.3.4 Preparation for MISPE procedure | 第114-120页 |
| 4.4. Conclusion | 第120-122页 |
| CHAPTER 5 STATE-OF-ART APPLICATIONS OF CYCLODEXTRINS ASFUNCTIONAL MONOMERS IN MOLECULAR IMPRINTING TECHNIQUES:AREVIEW | 第122-138页 |
| 5.1. Introduction | 第122-127页 |
| 5.2 Cyclodextrin(its derivative)-based imprinted polymers | 第127-132页 |
| 5.3 Combination of cyclodextrin(its derivative)and other functional monomers | 第132-136页 |
| 5.4 Conclusion | 第136-138页 |
| CHAPTER 6 OVERALL CONCLUSION AND FUTURE PROSPECTS | 第138-141页 |
| 6.1 Overall Conclusion | 第138-140页 |
| 6.2 Future prospects | 第140-141页 |
| REFERENCES | 第141-167页 |
