| Abstract | 第5-6页 |
| 摘要 | 第7-16页 |
| 1 Heterocyclic Compounds:A Brief Literature Review | 第16-50页 |
| 1.1 General Introduction | 第16页 |
| 1.2 Benzothiazoles/Benzimidazoles | 第16-26页 |
| 1.2.1 Biological Profile of Benzothiazoles | 第16-17页 |
| 1.2.2 Biological Profile of Benzimidazoles | 第17-18页 |
| 1.2.3 General Methods for the Preparation of Benzothiazoles/Benzimidazoles | 第18-21页 |
| 1.2.4 Classical Methods for the Synthesis of Benzothiazoles/Benzimidazoles | 第21-24页 |
| 1.2.5 Metal-Free Methods for Benzothiazoles and Benzimidazoles | 第24-25页 |
| 1.2.6 Synthesis of Benzothiazoles/Benzimidazoles from 2-Aminothiophenols/Anilines and β-Diketones | 第25-26页 |
| 1.3 Benzoxazoles | 第26-34页 |
| 1.3.1 Biological Profile of Benzoxazoles | 第26-27页 |
| 1.3.2 General Methods for the Synthesis of Benzoxazoles | 第27-31页 |
| 1.3.3 Classical Methods for the Synthesis of Benzoxazoles | 第31-33页 |
| 1.3.4 Synthesis of Benzoxazoles from 2-Aminophenols and β-Diketones | 第33-34页 |
| 1.4 Isoquinolones | 第34-47页 |
| 1.4.1 Biological Profile of Isoquinolones | 第34-35页 |
| 1.4.2 Classical Methods for the Synthesis of Isoquinolone | 第35-38页 |
| 1.4.3 Transition-Metal Catalyzed Synthesis of Isoquinolones | 第38-47页 |
| 1.4.4 Synthesis of Isoquinolone Derivatives from 2-Halobenzonitriles and Ketones | 第47页 |
| 1.5 Topic Selection and Research Motivation | 第47-50页 |
| 2 Convenient Synthesis of Benzothiazoles and Benzimidazoles through Br(?)nsted Acid-Catalyzed Cyclization of 2-Amino thiophenols/anilines with β-Diketones | 第50-65页 |
| 2.1 Introduction | 第50-51页 |
| 2.2 Experimental Section | 第51-57页 |
| 2.2.1 Materials and Instruments | 第51-53页 |
| 2.2.2 Representative Procedure for the Synthesis of Benzothiazoles | 第53页 |
| 2.2.3 Representative Procedure for the Synthesis of Benzimidazoles | 第53-54页 |
| 2.2.4 Characterization Data for All Products and Intermediate | 第54-57页 |
| 2.3 Results and Discussion | 第57-63页 |
| 2.3.1 Screening the Reaction Conditions for Benzothiazole Synthesis | 第57-58页 |
| 2.3.2 Substrate Scope Extension for Benzothiazoles | 第58-60页 |
| 2.3.3 Substrate Scope Extension for Benzimidazoles | 第60-63页 |
| 2.4 Reaction Mechanism | 第63-64页 |
| 2.5 Summary | 第64-65页 |
| 3 Synthesis of Benzoxazoles from 2-Aminophenols and β-Diketones Using a CombinedCatalyst of Br(?)nsted Acid and Cuprous Iodide | 第65-78页 |
| 3.1 Introduction | 第65页 |
| 3.2 Experimental Section | 第65-70页 |
| 3.2.1 Materials and Instruments | 第65-66页 |
| 3.2.2 Representative Procedure for the Synthesis of Benzoxazoles | 第66-67页 |
| 3.2.3 Characterization Data for All Products, Side Products and Intermediates | 第67-70页 |
| 3.3 Results and Discussion | 第70-75页 |
| 3.3.1 Screening the Conditions for Benzoxazole Synthesis | 第70-72页 |
| 3.3.2 Substrate Scope Extension for Benzoxazoles | 第72-75页 |
| 3.4 Reaction Mechanism for Benzoxazole Synthesis | 第75-77页 |
| 3.5 Summary | 第77-78页 |
| 4 Isoquinolone Synthesis through S_NAr Reaction of 2-Halobenzonitriles with Ketonesfollowed by Cyclization | 第78-93页 |
| 4.1 Introduction | 第78页 |
| 4.2 Experimental Section | 第78-83页 |
| 4.2.1 Materials and Instruments | 第78-80页 |
| 4.2.2 Representative Procedure for the Synthesis of Isoquinolones | 第80页 |
| 4.2.3 Characterization Data for All Products | 第80-83页 |
| 4.3 Results and Discussion | 第83-91页 |
| 4.3.1 Screening the Conditions for Isoquinolone Synthesis | 第83-86页 |
| 4.3.2 Scope for the Cyclization of 2-Bromobenzonitrile with Various Ketones | 第86-89页 |
| 4.3.3 Scope for the Cyclization of 2-Halobenzonitriles with Aromatic Ketones | 第89-91页 |
| 4.4 Reaction Mechanism | 第91-92页 |
| 4.5 Summary | 第92-93页 |
| 5 Conclusion | 第93-94页 |
| 6 Innovation Points and Future Horizons | 第94-96页 |
| 6.1 Innovation Points | 第94页 |
| 6.2 Future Horizons | 第94-96页 |
| References | 第96-104页 |
| Copies of NMR Spectra of Some Selected Compounds | 第104-114页 |
| Published Academic Papers during PhD Period | 第114-115页 |
| Acknowledgement | 第115-116页 |
| About the Author | 第116-118页 |
