| 中文摘要 | 第3-4页 |
| ABSTRACT | 第4-5页 |
| 1 INTRODUCTION | 第12-56页 |
| 1.1 GENERAL CHARACTERIZATION, PROPERTIES AND SYNTHESIS OF AZIDES | 第13-15页 |
| 1.1.1 Structure and properties | 第14-15页 |
| 1.1.2 Synthesis of aryl azides | 第15页 |
| 1.2 INTRODUCTION OF C-N3 BOND AND C-H BOND | 第15-16页 |
| 1.3 INTRODUCTION OF C-N3 BOND AND C-C BOND | 第16-33页 |
| 1.3.1 Construction of C-N3 bond and C-CN bond | 第22-27页 |
| 1.3.2 Construction of C-N3 bond and C-CF3 bond | 第27-33页 |
| 1.4 INTRODUCTION OF C-N3 BOND AND C-N BOND | 第33-38页 |
| 1.5 INTRODUCTION OF C-N3 BOND AND C-N3 BOND | 第38-44页 |
| 1.6 INTRODUCTION OF C-N3 BOND AND C-X BOND | 第44-45页 |
| 1.7 INTRODUCTION OF C-N3 BOND AND C-O BOND | 第45-54页 |
| 1.8 TOPIC AND ORGANIZATION OF THESIS | 第54-56页 |
| 2 COPPER CATALYZED DIFUNCTIONALIZATION OF ALKENES | 第56-82页 |
| 2.1 RESEARCH BACKGROUND | 第56-61页 |
| 2.2 THE STATEMENT CONCERNING SAFETY ISSUES | 第61-62页 |
| 2.3 OPTIMIZATION OF REACTION CONDITION | 第62-69页 |
| 2.3.1 Screening of Solvents, azide sources, and catalysts (Method A) | 第62-64页 |
| 2.3.2 Optimization amount of reagents, time and temperature | 第64-65页 |
| 2.3.3 Additives screening | 第65-66页 |
| 2.3.4 Screening of Solvents and catalysts (Method B) | 第66-68页 |
| 2.3.5 Optimization of Reaction Conditions (Method B) | 第68-69页 |
| 2.4 SUBSTRATE SCOPE METHOD A | 第69-71页 |
| 2.5 OXIDATIVE CLEAVAGE AND DEGRADED REARRANGEMENT | 第71页 |
| 2.6 SUBSTRATE SCOPE OF METHOD B | 第71-72页 |
| 2.7 NITRILE FORMATION FROM ALDEHYDE | 第72-73页 |
| 2.8 CONTROL EXPERIMENTS | 第73-74页 |
| 2.9 PROPOSED MECHANISM | 第74-75页 |
| 2.10 CONCLUSIONS | 第75页 |
| 2.11 EXPERIMENTAL SECTION | 第75-82页 |
| 2.11.1 General protocol for the preparation of alkene | 第75-76页 |
| 2.11.2 Method A: General procedure for synthesis of ketoazides | 第76页 |
| 2.11.3 Method B: General procedure for synthesis of ketoazides and aldehydes | 第76-77页 |
| 2.11.4 1H- and 13C-NMR analytical data | 第77-79页 |
| 2.11.5 1H- and 13C-NMR Spectra for new compounds | 第79-82页 |
| 3 COPPER CATALYZED OXYGENATION AND NITROGENATION OF ALKENES | 第82-100页 |
| 3.1 INTRODUCTION | 第82页 |
| 3.2 BACKGROUND | 第82-89页 |
| 3.3 SCREENING OF REAGENTS | 第89-90页 |
| 3.4 OPTIMIZATION OF AMOUNT OF REAGENTS, TIME AND TEMPERATURE | 第90-92页 |
| 3.5 SCREENING OF ADDITIVES | 第92-93页 |
| 3.6 SUBSTRATE SCOPE OF OXYGENATION AND NITROGENATION OF ALKENES | 第93-95页 |
| 3.7 CONTROL EXPERIMENTS | 第95-96页 |
| 3.8 PROPOSED MECHANISM | 第96页 |
| 3.9 CONCLUSION | 第96-97页 |
| 3.10 METHODS FOR THE PREPARATION OF 1,3-DIPHENYL PROPENE AND ITS DERIVATES | 第97页 |
| 3.11 EXPERIMENTAL SECTION | 第97-100页 |
| 3.11.1 General procedure for oxygenation and nitrogenation of olefins | 第97页 |
| 3.11.2 1H- and 13C-NMR analytical data | 第97-100页 |
| ACKNOWLEDGEMENTS | 第100-102页 |
| REFERENCES | 第102-112页 |
| APPENDIX | 第112-133页 |
| 4.1 PRODUCTS NMR SPECTRA | 第112-133页 |
| 4.2 THE AUTHOR’S SCIENTIFIC ACHIEVEMENTS DURING HIS PH.D | 第133页 |
