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Mathematical Models Behind Spread of HIV and Zika Virus Infections

Abstract第6-7页
Acknowledgements第8-9页
Dedication第9-16页
List of Abbreviations第16-17页
Chapter 1 Introduction and Overview第17-28页
    1.1 Overview of HIV Infections第18-21页
        1.1.1 Specific Achievements第19页
        1.1.2 UNAIDS Goal to end AIDS epidemic by 2030第19-20页
        1.1.3 Achievements in Botswana第20-21页
    1.2 Overview of ZIKV Infections第21-27页
        1.2.1 Regions Affected by ZIKV Infections第23-24页
        1.2.2 ZIKV Infections in Brazil第24-27页
    1.3 Dissertation Outline第27-28页
Chapter 2 Modeling and Simulation of UNAIDS Goal to end AIDS第28-50页
    2.1 Mathematical framework overview第29-30页
    2.2 Model Formulation第30-32页
    2.3 Estimation of Basic Reproduction Number,R_0第32-36页
        2.3.1 Role and Values of R_0第33-35页
        2.3.2 Variation of R_0 in Finite Size Population第35-36页
    2.4 Local Stability of Equilibrium Points the Model第36-41页
        2.4.1 Local Stability of the Disease Free Equilibrium Point第37-38页
        2.4.2 Local Stability of the Endemic Equilibrium of the Model第38-41页
    2.5 Simulation of the Model第41-49页
        2.5.1 UNAIDS Goal and Future of HIV in Botswana第44-48页
        2.5.2 Biological Health of Future Generation第48-49页
    2.6 Conclusion for Chapter 2第49-50页
Chapter 3 Modeling and Simulations of ZIKV Infections in Brazil第50-70页
    3.1 Mathematical Framework第51页
    3.2 Model Formulation第51-54页
    3.3 Analytic Analysis of the Model第54-61页
        3.3.1 The Basic Reproduction Number (R_0)第54-56页
        3.3.2 Stability of the Equilibrium Points第56-61页
        3.3.3 Estimation of ZIKV Infected Newborns (M)第61页
    3.4 Model Simulations第61-68页
        3.4.1 Fitting the Model into Brazil ZIKV Infections records第62-65页
        3.4.2 Natural Resistance Against ZIKV epidemics第65-66页
        3.4.3 Intervention for Epidemic Elimination第66-68页
    3.5 Conclusion for Chapter 3第68-70页
Chapter 4 Modified ZIKV Model第70-93页
    4.1 Theoretical Framework in Mathematical Perspective第71-72页
    4.2 Model Formulation第72-74页
    4.3 Model Analysis第74-88页
        4.3.1 Equilibrium Point and Basic Reproduction Number第74-76页
        4.3.2 Sensitivity Analysis of Basic Reproduction number (R_0)第76-86页
        4.3.3 Local Stability of the Endemic Equilibrium第86-88页
    4.4 Simulation of Spread of ZIKV Infections in Brazil第88-91页
    4.5 Discussions and Conclusion for Chapter 4第91-93页
Chapter 5 Thesis Discussion and Conclusion第93-97页
    5.1 Gaps in this Study第96-97页
References第97-106页
List of publications第106页

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