| 摘要 | 第4-6页 |
| Abstract | 第6-8页 |
| CHAPTER ONE | 第19-36页 |
| 1 Literature review | 第19-36页 |
| 1.1 The science of fluorescence method of sensing and fluorescent probes | 第19-20页 |
| 1.2 The 1,8-naphthalimide fluorophore | 第20-21页 |
| 1.3 Recent trends in the fluorescence sensing of some 1,8-naphthalimide-basedprobes for heavy metal ions, proton, and anions | 第21-35页 |
| 1.3.1 Some examples of fluorescent probes for selected metal ions | 第22-32页 |
| 1.3.1.1 Cu~(2+) ion-selective probes | 第22-24页 |
| 1.3.1.2 Hg~(2+)ion-selective probe | 第24-25页 |
| 1.3.1.3 Al~(3+)ion-selective probes | 第25-26页 |
| 1.3.1.4 Ag~+ ion-selective probe | 第26-27页 |
| 1.3.1.5 Zn~(2+)ion-selective probe | 第27-28页 |
| 1.3.1.6 Cr~(3+) ion-selective probes 101.3.1.7 Au~(3+)ion-selective probe | 第28-29页 |
| 1.3.1.7 Au~(3+)ion-selective probe | 第29-30页 |
| 1.3.1.8 Bi~(3+)ion-selective probe | 第30-31页 |
| 1.3.1.9 Multiple metal ions selective probes | 第31-32页 |
| 1.3.2 H~+ ion-selective probes | 第32-33页 |
| 1.3.3 Fluorescent probes for representative anions | 第33-35页 |
| 1.3.3.1 F-ion selective probe | 第33页 |
| 1.3.3.2 HSO_4~- ion-selective probe | 第33-34页 |
| 1.3.3.3 H_2PO_4~- ion-selective probe | 第34-35页 |
| 1.4 Sigificance and purpose the research work | 第35-36页 |
| CHAPTER TWO | 第36-66页 |
| 2 New highly potent 1,8-naphthalimide-based fluorescence 'turn off probes capable of Cu~(2+)ion detection in real-world water samples | 第36-66页 |
| 2.1 Introduction | 第36-37页 |
| 2.2 Experimental section | 第37-47页 |
| 2.2.1 Reagents and materials | 第37页 |
| 2.2.2 Instrumentation | 第37-38页 |
| 2.2.3 Photophysical properties | 第38页 |
| 2.2.4 Procedures for various titration experiments | 第38-41页 |
| 2.2.4.1 Effect of pH on the fluorescence intensity of Probes S1, S2, and S3 | 第38-39页 |
| 2.2.4.2 Influence of probe on the recognition of Cu~(2+) ion | 第39页 |
| 2.2.4.3 Fluorescence titration experiment | 第39-40页 |
| 2.2.4.4 UV-vis titration experiment | 第40页 |
| 2.2.4.5 Metal ion interference experiment | 第40页 |
| 2.2.4.6 Job plot titration experiment | 第40-41页 |
| 2.2.5 Syntheses of Probes S1, S2, and S3, and their characterisations | 第41-47页 |
| 2.2.5.1 Synthesis of intermediate Compounds 1(a-c) | 第42页 |
| 2.2.5.1.1 Synthesis of intermediate Compound 1-a | 第42页 |
| 2.2.5.1.2 Synthesis of intermediate Compound 1-b | 第42页 |
| 2.2.5.1.3 Synthesis of intermediate Compound 1-c | 第42页 |
| 2.2.5.2 Synthesis of intermediate Compounds 2(a-c) | 第42-44页 |
| 2.2.5.2.1 Synthesis of intermediate Compound 2-a | 第42-43页 |
| 2.2.5.2.2 Synthesis of intermediate Compound 2-b | 第43页 |
| 2.2.5.2.3 Synthesis of intermediate Compound 2-c | 第43-44页 |
| 2.2.5.3 Synthesis of intermediate Compounds 3(a-c) | 第44-45页 |
| 2.2.5.3.1 Synthesis of intermediate Compound 3-a | 第44页 |
| 2.2.5.3.2 Synthesis of intermediate Compound 3-b | 第44页 |
| 2.2.5.3.3 Synthesis of intermediate Compound 3-c | 第44-45页 |
| 2.2.5.4 Synthesis of Probes S1, S2, and S3, and their characterisations | 第45-47页 |
| 2.2.5.4.1 Synthesis of Probe N-allyl-4[-N-ethylenediamine-N,N-(di-3-propionic acid)]-1,8-naphthalimide (S1) | 第45页 |
| 2.2.5.4.2 Synthesis of Probe N-n-butyl-4-[-N-ethylenediamine-N,N-(di-3-propionic acid)]-1,8-naphthalimide (S2) | 第45-46页 |
| 2.2.5.4.3 Synthesis of Probe N-benzyl-4-[-N-ethylenediamine-N,N-(di-3-propionic acid)]-1,8-naphthalimide (S3) | 第46-47页 |
| 2.3 Results and discussion on Probes S1,S2, and S3 | 第47-65页 |
| 2.3.1 Design, synthesis, characterisation and solubility properties of Probes S1,S2,and S3 | 第47-48页 |
| 2.3.2 Photopphysical properties of Probes S2 and S3 | 第48-49页 |
| 2.3.3 Study of the pH effect on the spectral properties of Probes S1,S2, and S3 | 第49-52页 |
| 2.3.4 Identification properties of Probes S1, S2, and S3 towards Cu~(2+)ion | 第52-54页 |
| 2.3.5 Selectivity properties of Probes S1, S2, and S3 towards Cu~(2+)ion | 第54-55页 |
| 2.3.6 UV-vis and fluorescence titration experiments of Probes S1, S2, and S3 | 第55-60页 |
| 2.3.7 Binding ratios, association constants,and detection limits of Probes S1 S2,and S3 | 第60-62页 |
| 2.3.8 Insights into the binding modes of Probes S1, S2, and S3 with Cu~(2+) ion | 第62-64页 |
| 2.3.9 Applications of the proposed Probes S1,S2, and S3 for Cu~(2+)ion tracking | 第64-65页 |
| 2.4 Chapter summary | 第65-66页 |
| CHAPTER THREE | 第66-77页 |
| 3 Selective and sensitive fluorescence 'turn on'detection towards Hg~(2+) using1 ,8-naphthalimide and Schiff base | 第66-77页 |
| 3.1 Introduction | 第66-67页 |
| 3.2 Experimental section | 第67-71页 |
| 3.2.1 Reagents and materials | 第67页 |
| 3.2.2 Instrumentation | 第67-68页 |
| 3.2.3 Procedures for various titration experiments | 第68-69页 |
| 3.2.3.1 Effect of pH on the fluorescence intensity of Probe S4 | 第68页 |
| 3.2.3.2 Influence of Probe S4 on the recognition of Hg~(2+) ion | 第68页 |
| 3.2.3.3 Metal ion interference experiment | 第68页 |
| 3.2.3.4 Fluorescence titration experiment | 第68-69页 |
| 3.2.3.5 Job plot titration experiment | 第69页 |
| 3.2.4 Synthesis and characterisation of ProbeN-allyl-4-ethylenediamine-5-methylsalicylidene)-1,8-naphthalimide (S4) | 第69-71页 |
| 3.2.4.1 Synthesis of intermediate compound 4-a | 第70页 |
| 3.2.4.2 Synthesis of intermediate compound 4-b | 第70页 |
| 3.2.4.3 Synthesis of Probe S4 | 第70-71页 |
| 3.3 Results and discussion on Probe S4 | 第71-76页 |
| 3.3.1 Photophysical characteristics of Probe S4 | 第71-72页 |
| 3.3.2 Influence of pH on the photophysical properties of Probe S4 | 第72页 |
| 3.3.3 Fluorescence sensing behaviour of Probe S4 towards Hg~(2+)ion | 第72-76页 |
| 3.3.3.1 Recognition experiment of Probe S4 towards Hg~(2+)ion | 第72-73页 |
| 3.3.3.2 Selectivity experiment of Probe S4 towards Hg~(2+)ion | 第73-74页 |
| 3.3.3.3 Fluorescence titration experiment | 第74页 |
| 3.3.3.4 Job plot, association constant, and detection limit | 第74-76页 |
| 3.4 Chapter summary | 第76-77页 |
| CHAPTER FOUR | 第77-86页 |
| 4 A highly selective fluorescent'turn off' probe for the detection of picrate anion based on1,8-naphthalimide derivative | 第77-86页 |
| 4.1 Introduction | 第77-78页 |
| 4.2 Experimental section | 第78-80页 |
| 4.2.1 Reagents and materials | 第78页 |
| 4.2.2 Instrumentation | 第78页 |
| 4.2.3 Procedures for fluorescence measurement | 第78-79页 |
| 4.2.4 Synthesis and characterisation of ProbeN-allyl-4-iminodi(N-benzylacetamide)-1,8-naphthalimide (S5) | 第79-80页 |
| 4.2.4.1 Synthesis of iminodi(N-benzylacetamide) | 第79-80页 |
| 4.2.4.2 Synthesis of N-allyl-4-bromo-1,8-naphthalimide(intermediateCompound 5-a) | 第80页 |
| 4.2.4.3 Synthesis of the intended Probe S5 | 第80页 |
| 4.3 Results and disscussion Probe S5 | 第80-85页 |
| 4.3.1 Synthesis and solubility property of Probe S5 | 第80-81页 |
| 4.3.2 Fluorescence detection of picrate ion | 第81-82页 |
| 4.3.3 Fluorescence titration experiments | 第82-83页 |
| 4.3.4 Competition experiment | 第83-84页 |
| 4.3.5 Investigation of the sensing mechanism | 第84-85页 |
| 4.4 Chapter summary | 第85-86页 |
| General Conclusion | 第86-87页 |
| Acknowledgements | 第87-88页 |
| References | 第88-101页 |
| Appendix | 第101-110页 |
| Publications | 第110-111页 |
