| Acronyms | 第1-11页 |
| Abstract | 第11-13页 |
| Résumé | 第13-15页 |
| 摘要 | 第15-17页 |
| Part Ⅰ: Synthesis, electrochemical and fluorescence studies of 1,2,4,5-tetrazine derivatives: towards molecular sensors for anions and electron-rich compounds | 第17-187页 |
| Chapter 1 Introduction of 1,2,4,5-tetrazine chemistry and applications | 第19-49页 |
| ·Introduction of 1,2,4,5-tetrazines | 第19-20页 |
| ·Synthesis of tetrazines | 第20-27页 |
| ·Pinner synthesis | 第21-23页 |
| ·Ring closure of S-methylisothiocarbonohydrazide salt with orthoformate/ortho-acetates or iminium chlorides | 第23-24页 |
| ·Aromatic Nucleophilic Substitution (S_NAr reaction) | 第24-27页 |
| ·Reactivity of tetrazines | 第27-37页 |
| ·Aromatic nucleophilic substitution (S_NAr reaction) | 第27-29页 |
| ·Azaphilic addition with carbanions | 第29-30页 |
| ·Coss-coupling reactions with terminal alkynes | 第30-31页 |
| ·Inverse electron-demand Diels-Alder reaction | 第31-37页 |
| ·Research development and applications of tetrazines | 第37-44页 |
| ·Tetrazines as molecular models for theoretical studies | 第37-39页 |
| ·Tetrazine derivatives for NLO | 第39-40页 |
| ·Tetrazines in coordination chemistry | 第40-42页 |
| ·Tetrazines as energetic materials | 第42-43页 |
| ·Tetrazines as pharmaceuticals | 第43页 |
| ·Tetrazine derivatives for anticorrosion applications | 第43-44页 |
| References | 第44-49页 |
| Chapter 2 Development of anion and electron-rich compound sensors | 第49-69页 |
| ·Supramolecular chemistry and receptors | 第49页 |
| ·Optical(colorimetric, fluorescent)sensors and electrochemical sensors | 第49-53页 |
| ·Fluorescent molecular sensors | 第49-52页 |
| ·Electrochemical sensors | 第52-53页 |
| ·Anion sensors | 第53-62页 |
| ·Roles of anions | 第54页 |
| ·Difficulties in anion recognition and sensing | 第54-56页 |
| ·Developments in research for anion sensors | 第56-62页 |
| ·Sensors for electron-rich compounds | 第62-65页 |
| ·General Strategy used for detecting neutral analytes: π-π stacking | 第62-64页 |
| ·Rare examples of sensors for electron-rich compounds | 第64-65页 |
| References | 第65-69页 |
| Chapter 3 Tetrazine derivatives for sensor applications | 第69-83页 |
| ·Interaction of tetrazines with anions/electron-rich compounds—anion-π interaction/π-π interaction | 第69-70页 |
| ·Development of tetrazines in sensor applications: previous work in Audebert's group | 第70-75页 |
| ·Molecular designing of sensors | 第75-80页 |
| References | 第80-83页 |
| Chapter 4 Synthesis: results and discussion | 第83-107页 |
| ·Preparation of 3,6-dichloro-1,2,4,5-tetrazine | 第83-85页 |
| ·Attempts to synthesize novel tweezer molecular sensors | 第85-91页 |
| ·S_N Ar reaction of tetrazines | 第85-86页 |
| ·Tweezers with flexible chains | 第86-88页 |
| ·Tweezers with rigid frameworks | 第88-91页 |
| ·Synthesis of tripod molecular sensors | 第91-93页 |
| ·Using triethanolamine | 第91-92页 |
| ·Using 2-(bromomethyl)-2-(hydroxymethyl)propane-1,3-diol as triol | 第92-93页 |
| ·Synthesis of cyclophane molecular sensors | 第93-101页 |
| ·The first cyclophane-tetrazine | 第93-98页 |
| ·Attempt to synthesize cyclophane-tetrazine 92 | 第98-100页 |
| ·Reconsideration of cyclophane-tetrazine 90 | 第100-101页 |
| ·Synthesis of calycular molecular sensors: new multichromophoric cyclodextrin functionnalized by fluorescent tetrazine rings | 第101-105页 |
| ·Attachment of tetrazines onto cyclodextrins via S_NAr reactions | 第101-103页 |
| ·Attempt to attach tetrazines via "click chemistry" | 第103-105页 |
| References | 第105-107页 |
| Chapter 5 UV/Visible absorption, fluorescence and electrochemical studies | 第107-143页 |
| ·Introduction of fluorescence quenching: Stern-Volmer equation and Rehm-Weller equation | 第107-109页 |
| ·Spectroscopic and electrochemical study of tripod-tetrazine (86) | 第109-116页 |
| ·Absorption and fluorescence studies | 第110-111页 |
| ·Fluorescence quenching of tripod-tetrazine | 第111-114页 |
| ·Preliminary electrochemical studies of tripod-tetrazine | 第114-116页 |
| ·Spectroscopic and electrochemical studies of the first cyclophane (93) | 第116-120页 |
| ·Spectroscopic study | 第116-117页 |
| ·Electrochemistry study | 第117-118页 |
| ·Sensitivity of the electrochemical response to added organic compounds | 第118-120页 |
| ·Discussion of fluorescence of new cyclophane-tetrazine (90) and tetrazine 118 and 128 | 第120-130页 |
| ·Trimer-tetrazine 118 | 第120-123页 |
| ·Cyclophane-tetrazine 90 | 第123-125页 |
| ·Tetrazine 128 | 第125-126页 |
| ·Molecular modeling and fluorescence properties | 第126-130页 |
| ·Fluorescence and electrochemical study of β-CD-tetrazine | 第130-135页 |
| ·Absorption and fluorescence studies | 第130-132页 |
| ·Fluorescence quenching of β-CD-tetrazine | 第132-134页 |
| ·Electrochemical study of β-CD-tetrazine | 第134-135页 |
| ·α-CD-tetrazine (95) | 第135-141页 |
| ·Absorption and fluorescence studies of 95 | 第135-136页 |
| ·Fluorescence quenching | 第136-138页 |
| ·Electrochemical study | 第138-141页 |
| References | 第141-143页 |
| General conclusion | 第143-145页 |
| Chapter 6 Experimental Section | 第145-187页 |
| Part Ⅱ: Synthesis and electrochemical study of ferrocene-containing pyridinium salts | 第187-239页 |
| Chapter 1 Introduction | 第189-207页 |
| ·Introduction of ferrocene | 第189页 |
| ·Basic electrochemical behavior | 第189-190页 |
| ·Development in research of molecules containing multiple ferrocenes | 第190-203页 |
| ·Molecules containing two ferrocene units | 第190-193页 |
| ·Molecules containing multiple ferrocene units | 第193-199页 |
| ·Dendrimers containing ferrocenes | 第199-203页 |
| References | 第203-207页 |
| Chapter 2 Molecular design of ferrocene-containing pyridinium salts | 第207-211页 |
| ·Previous work in Tang's group | 第207-208页 |
| ·Molecular design | 第208-210页 |
| References | 第210-211页 |
| Chapter 3 Results and discussion | 第211-227页 |
| ·Synthesis of dibranched and tribranched pyridiniums | 第211-219页 |
| ·Improvement of synthesis of trans-5-(2-ferrocenyl-vinyl)-2-carbaldehyde-thiophene | 第211-212页 |
| ·Influence of base for Wittig olefination | 第212-213页 |
| ·Isomerization of Z-isomers to E-isomers with I_2 | 第213-214页 |
| ·Condensation of aromatic aldehyde with multimethyl-pyridiniums | 第214-219页 |
| ·Electrochemical results and discussion | 第219-226页 |
| ·Preliminary electrochemical study of 45i and 46i | 第219-220页 |
| ·Preliminary electrochemical study of 45h | 第220-221页 |
| ·Preliminary electrochemical study of 46h | 第221-222页 |
| ·Preliminary electrochemical study of 45j | 第222-224页 |
| ·Preliminary electrochemical study of 46j | 第224-226页 |
| References | 第226-227页 |
| General conclusion | 第227-229页 |
| Chapter 4 Experimental section | 第229-239页 |
| List of publications | 第239-241页 |
| Acknowledgement | 第241-242页 |
