| 摘要 | 第3-5页 |
| Abstract | 第5-7页 |
| Abbreviations | 第10-11页 |
| Part Ⅰ Introduction | 第11-27页 |
| 1.1 The background of early social environment | 第12-15页 |
| 1.1.1 Biparental care (PC) | 第12-14页 |
| 1.1.2 Paternal deprivation (PD) | 第14-15页 |
| 1.2 Social recognition | 第15-17页 |
| 1.3 The influence of early social environment on Social recognition | 第17-18页 |
| 1.4 The influence of early social environment on neuroendocrine system | 第18-21页 |
| 1.5 Oxytocin (OT), Oxytocin receptor (OTR) and Social recognition | 第21-23页 |
| 1.6 Estrogen receptor alpha (ERa) and Social recognition | 第23-24页 |
| 1.7 The model animal:Mandarin vole | 第24-25页 |
| 1.8 Research significance and the goal of study | 第25-27页 |
| Part Ⅱ Materials and methods | 第27-33页 |
| 2.1 Subjects | 第27页 |
| 2.2 Treatment | 第27-28页 |
| 2.3. Social Recognition Test | 第28页 |
| 2.4 Serum and MeA and NAcc tissue collection | 第28-29页 |
| 2.5 Quantification of OT | 第29页 |
| 2.6 RNA extraction | 第29-30页 |
| 2.7 Real-time quantitative polymerase chain reaction analysis | 第30页 |
| 2.8 Statistical analyses | 第30-33页 |
| Part Ⅲ Results | 第33-41页 |
| 3.1 The effect of PD on social recognition in female voles | 第33-34页 |
| 3.2 The effect of PD on social recognition in male voles | 第34-37页 |
| 3.3 Serum OT levels in PC and PD groups | 第37页 |
| 3.4 OTR and ERa mRNA expression in the MeA and NAcc in PC and PD groups | 第37-41页 |
| Part Ⅳ Discussion | 第41-49页 |
| 4.1 Effects of paternal deprivation on social recognition behavior | 第41-43页 |
| 4.2 Effects of paternal deprivation on levels of serum oxytocin (OT) and oxytocinreceptors mRNA expression in MeA and NaCC | 第43-44页 |
| 4.3 The relationship between OT and OTR in MeA and NaCC and social recognition | 第44-45页 |
| 4.4 Effects of paternal deprivation on levels of estrogen receptors mRNA expressionin MeA | 第45-47页 |
| 4.5 The relationship between ERα in MeA and social recognition | 第47页 |
| 4.6 The relationship between OT/OTR and ERα/ERβ in social recognition | 第47-48页 |
| 4.7 The problems and prospects | 第48-49页 |
| Conclusions | 第49-51页 |
| References | 第51-69页 |
| Plates | 第69-71页 |
| Acknowledgments | 第71-73页 |
| List of publications | 第73页 |
