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Effects of Selenium-enriched Probiotics on Murine Lipid Metabolism Abnormality, Pathological Lesions and Potential Male Infertility Induced by Feeding a High Fat Diet

Abstract第10-12页
摘要第13-16页
Abbreviations第16-20页
Introduction第20-25页
Part One Review of Literature第25-87页
    Chapter 1 Review of Literature: Lipid and hyperlipidemia第25-41页
        1.1. Lipids第25-30页
        1.2. Lipid metabolism第30-32页
        1.3. Hyperlipidemia第32-36页
            1.3.1. Classification of hyperlipidaemia第32-33页
            1.3.2. Signs and Symptoms第33页
            1.3.3. Differential Diagnosis第33-34页
            1.3.4. Diagnosis第34页
            1.3.5. Common current treatment of hyperlipidemia第34页
            1.3.6. Dietary Interventions第34-36页
        Reference第36-41页
    Chapter 2 Review of Literature: Male fertility第41-49页
        2.1. Mammalian spermatozoa第41页
        2.2. Male infertility第41-43页
            2.2.1. Factors relating to male infertility第41-42页
            2.2.2. Diagnosis第42页
            2.2.3. Defective sperm function第42-43页
        2.3. Cholesterol and spermatozoa第43页
        2.4. Hyperlipidemia and male infertility第43-45页
        References第45-49页
    Chapter 3 Review of Literature: Selenium第49-71页
        3.1. Introduction第49页
        3.2. History and global demand第49页
        3.3. Dietary sources of Se第49页
        3.4. Deficiency第49-50页
        3.5. Toxicity第50页
        3.6. Se Forms第50页
        3.7. Supplements第50-51页
        3.8. Selenoproteins第51页
        3.9. Absorption第51页
        3.10. Metabolism第51-52页
        3.11. Excretion第52页
        3.12. Antioxidant enzyme第52-53页
        3.13. Antioxidant nutrients第53页
        3.14. Health effects and nutrition第53-54页
        3.15. Studies on the effect of Se on lipid metabolism第54-57页
        3.16. Studies on the effect of Se on fertility第57-59页
        References第59-71页
    Chapter 4 Review of Literature: Probiotic第71-87页
        4.1. Introduction第71-72页
        4.2. Back ground about Probiotics第72页
        4.3. History第72页
        4.5. Available form第72-74页
        4.10. Candida(fungus)第74-76页
        4.11. Effect of probiotic on lipid metabolism第76页
        4.12. Studies on hypolipidemic effect of probiotic第76-80页
        References第80-87页
Part TwoResearch Work第87-165页
    Chapter 5 Effect of selenium-enriched probiotics on lipid metabolismin mice fed a high fat diet and its mechanism第87-120页
        Abstract第87-88页
        5.1. Introduction第88-90页
        5.2. Materials and methods第90-99页
        5.3. Results第99-105页
            5.3.1. Serum Se Level第99-100页
            5.3.2. Serum Lipid profile第100-101页
            5.3.3. Php LPL level第101页
            5.3.4. Serum T4 and T3 levels第101-102页
            5.3.5. The specificity of the primers and identification of the plasmids第102-105页
        5.4. Discussion第105-111页
        5.5. Conclusion第111页
        References第111-120页
    Chapter 6 Effects of selenium-enriched probiotics on healthperformance, macro and micropathology in mice fed a highfat diet第120-143页
        Abstract第120-121页
        6.1. Introduction第121页
        6.2. Material and Methods第121-124页
            6.2.1. Animals & feeding第121-122页
            6.2.2. Experimental Design第122页
            6.2.3. Health performance and body weight gain第122页
            6.2.4. Pathological examinations第122-123页
            6.2.5. Statistical analysis第123-124页
        6.3. Results第124-136页
            6.3.1. Gain in body weight第124页
            6.3.2. Health performance第124页
            6.3.3. Post-mortem findings第124-136页
        6.4. Discussion第136-138页
        6.5. Conclusions第138-139页
        References第139-143页
    Chapter 7 Selenium-enriched probiotics alleviate murine male fertilitycompromised by high fat diet第143-165页
        Abstract第143-144页
        7.1. Introduction第144-145页
        7.2. Materials and methods第145-148页
            7.2.1. Animals & feeding第145页
            7.2.2. Experimental Design第145-146页
            7.2.3. Blood collection第146页
            7.2.4. Serum Testosterone第146-147页
            7.2.5. Sex organs and semen evaluations第147页
            7.2.6. Histopathology第147页
            7.2.7. Statistical analysis第147-148页
        7.3. Results第148-155页
            7.3.1. Serum Testosterone Level第148页
            7.3.2. Sperm index第148-151页
            7.3.3. Sex organs第151-155页
        7.4. Discussion第155-159页
        7.6. In conclusion第159页
        References第159-165页
Summary第165-167页
New knowledge第167-168页
Research implication第168-169页
Missing Links & Future Research Opportunities第169-170页
Publications第170-171页
Acknowledgements第171-172页

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