| 英文摘要 | 第8页 |
| Chapter 1 INTRODUCTION: CONCEPT OF MARKER-ASSISTED SELECTION;IMPORTANCE OF EPISTASIS AND GENOTYPE×ENVIRONMENT INTERACTION; PURPOSE OF THIS RESEARCH | 第13-16页 |
| Chapter 2 LITERATURE REVIEW: ADVANCES ON MARKER-ASSISTED SELECTION IN THE IMPROVEMENT OF QUANTITATIVE TRAITS | 第16-37页 |
| 2．1 GENETIC MARKERS | 第16-19页 |
| 2．2 FUNDAMENTALS OF MARKER-ASSISTED SELECTION | 第19-20页 |
| 2．3 MARKER-ASSISTED BACKCROSSING | 第20-23页 |
| 2．4 MARKER-ASSISTED INDEX SELECTION | 第23-26页 |
| 2．5 MARKER-ASSISTED BEST LINEAR UNBIASED PREDICTION | 第26-29页 |
| 2．6 GENOMIC SELECTION | 第29-31页 |
| 2．7 PRACTICAL APPLICATIONS OF MARKER-ASSISTED SELECTION IN PLANT BREEDING | 第31-34页 |
| 2．8 SYNERGY OF EMPIRICAL BREEDING, MARKER-ASSISTED SELECTION, AND GENOMICS IN THE IMPROVEMENT OF QUANTITATIVE TRAITS | 第34-37页 |
| Chapter 3 A METHOD FOR MARKER-ASSISTED SELECTION BASED ON QTLS WITH EPISTATIC EFFECTS | 第37-56页 |
| 3．1 INTRODUCTION | 第37-39页 |
| 3．2 METHODS | 第39-41页 |
| 3．2．1 Genetic model | 第39-40页 |
| 3．2．2 Estimation of breeding value | 第40-41页 |
| 3．3 SIMULATION | 第41-45页 |
| 3．3．1 Genetic map | 第41-42页 |
| 3．3．2 Generating phenotypic data | 第42-43页 |
| 3．3．3 Effects of inaccurate parameter estimates on the genetic response to MAS | 第43-44页 |
| 3．3．4 Selection | 第44-45页 |
| 3．4 RESULTS | 第45-53页 |
| 3．4．1 Genetic response to MAS with epistasis | 第45-50页 |
| 3．4．1．1 Genetic response | 第45-46页 |
| 3．4．1．2 Breeding value as a measure for selection | 第46-49页 |
| 3．4．1．3 Genetic variance configurations | 第49-50页 |
| 3．4．2 Effects of inaccurate estimates on the genetic response to MAS | 第50-53页 |
| 3．4．2．1 QTL position | 第51页 |
| 3．4．2．2 QTL effect | 第51页 |
| 3．4．2．3 False positive QTL | 第51-53页 |
| 3．5 DISCUSSION | 第53-56页 |
| Chapter 4 IMPACTS OF QTL×ENVIRONMENT INTERACTIONS ON GENETIC RESPONSE TO MARKER-ASSISTED SELECTION | 第56-70页 |
| 4．1 INTRODUCTION | 第56-58页 |
| 4．2 METHODS | 第58-60页 |
| 4．2．1 Genetic model | 第58-59页 |
| 4．2．2 Estimation of breeding value | 第59-60页 |
| 4．3 SIMULATION | 第60-63页 |
| 4．3．1 Genetic map | 第60页 |
| 4．3．2 Generating phenotypic data | 第60-62页 |
| 4．3．3 Selection | 第62-63页 |
| 4．4 RESULTS | 第63-67页 |
| 4．4．1 Breeding experiments conducted in one location throughout | 第63-65页 |
| 4．4．2 Breeding experiments conducted in two locations alternately | 第65-67页 |
| 4．5 DISCUSSION | 第67-70页 |
| Chapter 5 MARKER-ASSISTED SELECTION IN SEGREGATING GENERATIONS OF SELF-FERTILIZING CROPS | 第70-87页 |
| 5．1 INTRODUCTION | 第70-72页 |
| 5．2 METHODS | 第72-74页 |
| 5．2．1 QTL genorype conditioned on its marker type and phenotype | 第72页 |
| 5．2．2 Potential index | 第72-73页 |
| 5．2．3 Marker index | 第73-74页 |
| 5．3 SIMULATION | 第74-76页 |
| 5．3．1 Selection methods | 第74-75页 |
| 5．3．2 Outcomes of selection | 第75-76页 |
| 5．4 RESULTS | 第76-83页 |
| 5．4．1 Selection in early generations | 第76-78页 |
| 5．4．2 Selection in later generations | 第78-80页 |
| 5．4．3 Selection ir full generations | 第80-81页 |
| 5．4．4 Efficiency or a modified method combining MAS in early generations with Phenotypic selection in later generations | 第81-83页 |
| 5．5 DISCUSSION | 第83-87页 |
| SUMMARY | 第87-90页 |
| Appendix A DERIVATION OF AN APPROXIMATION FOR p（z_i|h_i） | 第90-95页 |
| A．1 ESTIMATING THE PROBABILITY OF QTL GENOTYPE CONDITIONED ON ITS FRANKING MARKER GENOTYPES p（z_i|h_（i_1）,h_（i_2）） | 第90-91页 |
| A．2 DEALING WITH DOUBLE HETEROZYGOTE | 第91-92页 |
| A．3 ESTIMATING OF THE FREQUENCIES OF QTL ALLELE | 第92-95页 |
| Appendix B AN ALGORITHM TO CALCULATE MULTI-LOCUS GAMETE FREQUENCIES FOR SELF-FERTILIZATION | 第95-100页 |
| REFERENCES | 第100-115页 |
