| List of figures | 第1-8页 |
| List of tables | 第8-9页 |
| ABSTRACT IN CHINESE | 第9-11页 |
| ABSTRACT | 第11-13页 |
| Chapter 1 Introduction | 第13-41页 |
| Ⅰ Overview of the adaptive marker: MHC | 第13-28页 |
| Structure and function | 第14-17页 |
| MHC evolution | 第17-19页 |
| MHC polymorphism and selection mechanisms | 第19-22页 |
| Test for selection and outcomes in studies of natural populations | 第22-24页 |
| Importance of MHC variability in conservation | 第24-28页 |
| Ⅱ Background, goals and organizations of the dissertation | 第28-31页 |
| Background of the dissertation | 第28-30页 |
| Technical routes | 第30-31页 |
| Refernces | 第31-41页 |
| Chapter 2 Sequence Variability and Evolution at Three MHC Loci of Finless Porpoises | 第41-68页 |
| Abstract | 第41-42页 |
| Introduction | 第42-43页 |
| Materials and methods | 第43-47页 |
| Samples | 第43-44页 |
| DNA isolation and PCR | 第44-46页 |
| SSCP, cloning and sequencing | 第46页 |
| Data analysis | 第46-47页 |
| Results | 第47-58页 |
| Number of unique sequences at three MHC loci | 第47-51页 |
| Network analysis and phylogenetic reconstruction | 第51-52页 |
| Sequence variability of three MHC loci | 第52-58页 |
| Discussion | 第58-62页 |
| Gene duplication and genetic variation of MHC genes in finless porpoises | 第58-60页 |
| Balancing selection | 第60-61页 |
| Trans-species or convergent evolution between the finless porpoise and baiji | 第61-62页 |
| References | 第62-68页 |
| Chapter 3 High Similarity at Three MHC Loci between the Baiji and Finless Porpoise: Trans-speeies or Convergent Evolution? | 第68-90页 |
| Abstract | 第68-69页 |
| Introduction | 第69-71页 |
| Materials and methods | 第71-72页 |
| Samples | 第71页 |
| Data analysis | 第71-72页 |
| Results | 第72-82页 |
| Allelic diversity of two MHC genes | 第72-74页 |
| Phylogenetic reconstruction | 第74-75页 |
| Similar and identical alleles between the baiji and finless porpoise | 第75-80页 |
| Mismatch distributions and intragenic recombination analyses | 第80-82页 |
| Discussion | 第82-85页 |
| Genetic variation of the MHC genes | 第82-83页 |
| Population expansion and intragenic recombination | 第83页 |
| High similarity betweetn the baiji and finless porpoise: convergent evolution? | 第83-85页 |
| References | 第85-90页 |
| Chapter 4 Sequence Variability at Three Cetacean MHC Loci | 第90-111页 |
| Abstract | 第90-91页 |
| Introduction | 第91页 |
| Materials and methods | 第91-94页 |
| Samples | 第92页 |
| DNA isolation and PCR | 第92页 |
| SSCP, cloning and sequencing | 第92-93页 |
| Data analysis | 第93-94页 |
| Results | 第94-102页 |
| Sequence diversity of three MHC loci | 第94-97页 |
| Phyiogenetic reconstruction | 第97-102页 |
| Discussion | 第102-106页 |
| References | 第106-111页 |
| Conclusion and Future Research | 第111-114页 |
| Publication List | 第114-115页 |
| Acknowledgements | 第115页 |
