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Relationship between the Structure and Mechanical Properties of PLC Prototype Vascular Graft Reinforced with Knitted Pet Fabric

ACKNOWLEDGEMENTS第6-7页
ABSTRACT第7-8页
TABLE OF CONTENT第9-17页
ABBREVIATION第17-18页
LIST OF TABLES第18-20页
LIST OF FIGURES第20-24页
CHAPTER 1. INTRODUCTION AND BACKGROUND第24-27页
    1.1. Background第24-25页
    1.2. Purpose and Objective of the Study第25页
    1.3. Definitions第25页
    1.4. Methodology第25-27页
CHAPTER 2.LITERATURE REVIEW第27-55页
    2.1. Introduction第27-28页
    2.2. The Morphology of Blood Vessels第28-30页
        2.2.1. The Wall Structure of the Blood Vessel第29-30页
    2.3. Hardening of the Arteries (Arteriosclerosis, Plaque Buildup)第30-32页
        2.3.1. Causes, Incidence and Risk Factors第30-31页
        2.3.2. Symptoms第31页
        2.3.3. Signs and Tests第31页
        2.3.4. Treatment第31-32页
    2.4. Vascular Grafts第32-36页
        2.4.1. Biological Prosthetic Grafts第32-35页
        2.4.2. Tissue Engineered Vascular Graft第35-36页
    2.5. Polymeric Biomaterials第36-42页
        2.5.1. Nonabsorbable Polymers第38-39页
        2.5.2. Biodegradable Polymers第39-42页
    2.6. Fabric Structure第42-48页
        2.6.1. Woven第43-44页
        2.6.2. Knitted第44-46页
        2.6.3. Braided第46-47页
        2.6.4. Non-woven第47-48页
    2.7. Surface Modification第48-52页
        2.7.1. Surface Modification of Polyester第48-49页
        2.7.2. Surface Modification of Expanded Polytetrafluoroethylene(ePTFE)第49页
        2.7.3. Surface Modification of Polyurethane(PU)第49-50页
        2.7.4. Surface Modification of Polycaprolactone(PCL)第50-52页
    2.8. Mechanical Properties第52-53页
        2.8.1. Circumferential Tensile Strength第53页
        2.8.2. Longitudinal Tensile Strength第53页
        2.8.3. Kink Radius第53页
        2.8.4. Dynamic Compliance第53页
    2.9. Problems of Current Grafts第53-55页
CHAPTER 3. EXPERIMENTAL DESIGN,MATERIALS ANDMETHOD第55-76页
    3.1. Materials第55-57页
        3.1.1. Polyester第55-56页
        3.1.2. PCL第56页
        3.1.3. Organic Solvents第56-57页
        3.1.4. Sutures第57页
    3.2. Samples Preparation第57-61页
        3.2.1. Knitted Fabric Tube第57-59页
        3.2.2. Solution Preparation第59页
        3.2.3. Compositing Process第59-60页
        3.2.4. Drying Process第60-61页
    3.3. Experimental Design第61-64页
        3.3.1. PCL Films第61-62页
        3.3.2. Composition and Their Biomechanical Properties第62-63页
        3.3.3. Influence of the Molecular Weight on the Biomechanical Properties第63页
        3.3.4. Influence of the Fabric Density on the Biomechanical Properties第63-64页
    3.4. Characterization Techniques第64-75页
        3.4.1. Yarn Characterization第64-65页
        3.4.2. Optical Microscope第65页
        3.4.3. X-ray diffraction第65页
        3.4.4. Geometrical Characteristic第65-67页
        3.4.5. Microstructure第67页
        3.4.6. Tensile Strength第67-70页
        3.4.7. Water Permeability第70-71页
        3.4.8. Elastic Recovery第71-73页
        3.4.9. Suture Retention Strength第73-74页
        3.4.10. Dynamic Compliance Properties第74-75页
    3.5. Summary第75-76页
CHAPTER 4. PREPARATION AND CHARACTERIZATION OFSMALL DIAMETER PROTOTYPE VASCULAR GRAFT第76-96页
    4.1. Preparation第76-81页
        4.1.1. Tubular Fabric Characterization第76-78页
        4.1.2. Selection of the Solvent第78-80页
        4.1.3. Preparation of Small Diameter Prototype Vascular Graft第80-81页
    4.2. Biomechanical Properties第81-95页
        4.2.1. Geometric Characteristic第81-82页
        4.2.2. Microstructure第82-84页
        4.2.3. Tensile Strength第84-88页
        4.2.4. Water Permeability第88-89页
        4.2.5. Elastic recovery第89-91页
        4.2.6. Suture Retention Strength第91-93页
        4.2.7. Dynamic Compliance Properties第93-95页
    4.3. Summary第95-96页
CHAPTER 5. INFLUENCE OF MATERIAL PARAMETERS AND TEXTILE STRUCTURE ON THE PROPERTIES OFPCL/PET COMPOSITE PROTOTYPE VASCULAR GRAFTS第96-107页
    5.1. Influence of the PCL Molecular Wei ght on the Biomechanical Properties第96-102页
        5.1.1. Influence of the Molecular Weight on the Geometrical Characteristic第96-98页
        5.1.2. Influence of the Molecular Weight on the Microstructure第98-99页
        5.1.3. Influence of the Molecular Weight on the Breaking Strength第99-100页
        5.1.4. Influence of the Molecular Weight on the Elastic Recovery第100-102页
    5.2. Influence of the Fabric Density on the Biomechanical Properties第102-106页
        5.2.1. Influence of the Fabric Density on the Geometrical Characteristic第102-103页
        5.2.2. Influence of the Fabric Density on the Breaking Strength第103-104页
        5.2.3. Influence of the Fabric Density on the Elastic Recovery第104-105页
        5.2.4. Influence of the Fabric Density on the Suture Retention Strength第105-106页
    5.3. Summary第106-107页
CHAPTER 6. CONCLUSION AND PROSPECTS第107-109页
    6.1. Conclusion第107-108页
    6.2. Future Work第108-109页
REFERENCES第109-119页
PUBLICATION DURING GRADUATE STUDY第119页

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