| 中文摘要 | 第3-7页 |
| ABSTRACT | 第7-8页 |
| Chapter1.Literature Review | 第11-33页 |
| 1.1 Introduction | 第11页 |
| 1.2 Representative Biological or Natural Compounds Bearing an N-Alkoxyinodole | 第11-12页 |
| 1.3 Representative Pharmaceutical Agents Containing of the N-Alkoxyinodole Framework | 第12-13页 |
| 1.4 General Strategies for the Construction of the N-Alkoxyinodole Skeleton | 第13-22页 |
| 1.4.1 Synthesis of N-Methoxyindole Derivatives via Methylation of N-Hydroxyindoles(path a) | 第14-18页 |
| 1.4.2 Dihydroindoles Dehydration Reaction to Synthesis of N-Methoxyindole(path b) | 第18页 |
| 1.4.3 Sodium Chloride/Thionyl Chloride Mediated Cyclization of the Requisite two Electron-withdrawing Substituents Functionalized Substrate(bath c) | 第18-19页 |
| 1.4.4 Synthesis of N-Methoxyindoles Compounds by Cycloaddition of Nitro-and Nitrosoaromatics with Alkynes(path d) | 第19-20页 |
| 1.4.5 Synthesis of N-Methoxyindoles Compounds by Cycloaddition of O-Methyloxime with Dimethyl Sulfoxide(path e) | 第20-21页 |
| 1.4.6 Synthesis of N-Alkoxyindoles via Intramolecular Heterocyclization of 3-Alkoxyimino-2-arylalkylnitriles Mediated by FeCl_3 | 第21-22页 |
| 1.5 Introduction of the Hypervalent Iodine Reagent(Ⅲ)Dichlorobenzene | 第22-24页 |
| 1.6 Synthetic Application of Dichloro Iodobenzene Compounds | 第24-31页 |
| 1.6.1 Synthesis of Dichlorobenzene as an Oxidant | 第24-25页 |
| 1.6.2 Regioselective Chloroformyloxylation of Alkenes by PhICl_2 Mediated | 第25-27页 |
| 1.6.3 Oxidation and Chlorination ofα,N-Dichloroimines | 第27-28页 |
| 1.6.4 Oxidative Rearrangement of Primary Alcohols Using PhICl_2-NaN_3 | 第28-29页 |
| 1.6.5 Thiocyanation of Phenol Using PhICl_2-Pb(SCN)_2 | 第29-30页 |
| 1.6.6 Regioselective Chlorination of Aromatic Ketones Using PhICl_2 | 第30页 |
| 1.6.7 Combination of PhICl_2 and Metal | 第30-31页 |
| 1.7 Chapter Summary | 第31-33页 |
| Chapter2.Projects Design | 第33-39页 |
| 2.1 Introduction | 第33页 |
| 2.2 Project Design | 第33-37页 |
| 2.3 Preliminary Research Results | 第37-38页 |
| 2.4 Research Contents | 第38-39页 |
| Chapter3.Results and Discussion | 第39-51页 |
| 3.1 Introduction | 第39页 |
| 3.2 Discovery of the Reaction and the Identification of the Structure of the Product | 第39-40页 |
| 3.3 Optimization of Reaction Conditions and Discussion | 第40-41页 |
| 3.4 Discussion on the Scope of Application of the Reaction Substrates | 第41-43页 |
| 3.5 Investigate the Generality of this Newly Established Method | 第43-46页 |
| 3.6 Study on Applications of Reaction | 第46-47页 |
| 3.7 Mechanism of Discussion | 第47-48页 |
| 3.8 Chapter Summary | 第48-51页 |
| Chapter4.Conclusion | 第51-53页 |
| Chapter5.Experimental Section | 第53-61页 |
| 5.1.General Information | 第53页 |
| 5.2.Source and Specification of Reagents | 第53-55页 |
| 5.3 Analytical Instruments and Methods | 第55页 |
| 5.4 General Procedure | 第55-60页 |
| 5.4.1 General Procedure for the Synthesis of Ketonitriles | 第55-56页 |
| 5.4.2 General Procedure for the Preparation of Substrates 99 | 第56页 |
| 5.4.3 Preparation of the Chlorinated Intermediate 108 | 第56-57页 |
| 5.4.4 General One-pot Procedure for the Preparation of N-Alkoxyindole-3-carbonitriles 101 | 第57-58页 |
| 5.4.5 Synthesis of2-Methyl-1H-indole-3-carbonitrile 109 | 第58-59页 |
| 5.4.6 Synthesis of1-Methoxy-2-methyl-1H-indole-3-carboxamide 110 | 第59页 |
| 5.4.7 Synthesis of1-Hydroxy-2-methyl-1H-indole-3-carbonitrile 111 | 第59-60页 |
| 5.4.8 Synthesis of Iodobenzene Dichloride | 第60页 |
| 5.5 Chapter Summary | 第60-61页 |
| Chapter6.Spectroscopic Data of Substrates and Products | 第61-81页 |
| 6.1 Spectroscopic Data of 3-Alkoxyimino-2-aryl-alkylnitrilles 99 | 第61-70页 |
| 6.2 Spectroscopic Data of the Chlorinated Intermediate 108 | 第70页 |
| 6.3 Spectroscopic Data of N-Alkoxyindole-3-carbonitriles 101 | 第70-79页 |
| 6.4 Spectroscopic Data of Derivatization of N-Alkoxyindoles | 第79-81页 |
| References | 第81-95页 |
| Appendix: Compound ~1H and~(13)C-NMR Spectra | 第95-145页 |
| Notes on Publications and Participation in Scientific Research | 第145-147页 |
| Acknowledgements | 第147-148页 |
