| 摘要 | 第3-7页 |
| ABSTRACT | 第7-8页 |
| Chapter 1 Research Background | 第11-37页 |
| 1.1 Biologically Active Pharmaceutical Spirooxindoles | 第11页 |
| 1.2 Synthetic Routes of Spirooxindoles | 第11-19页 |
| 1.2.1 Prepare Spirooxindoles via [3+2] Cycloaddition Reactions | 第11-13页 |
| 1.2.2 Prepare Spirooxindoles via Radical Cycloaddition Reactions | 第13-15页 |
| 1.2.3 Prepare Spirooxindoles via Organometallic Catalyst | 第15-17页 |
| 1.2.4 Prepare Spirooxindoles via Non-metal Catalytic Synthesis | 第17-19页 |
| 1.3 The Application of Hypervalent Iodine Reagents in Organic Synthesis | 第19-33页 |
| 1.3.1 Hypervalent Iodine Reagents Mediated Oxidation Reaction | 第20-21页 |
| 1.3.2 Hypervalent Iodine Reagents Mediated Oxidative Coupling Reaction | 第21-25页 |
| 1.3.3 Hypervalent Iodine Reagents Mediated Functional Group Transfer Reaction | 第25-26页 |
| 1.3.4 Hypervalent Iodine Reagents Mediated Dearomatization Reaction | 第26-29页 |
| 1.3.5 Hypervalent Iodine Reagents Mediated Rearrangement Reaction | 第29-33页 |
| 1.4 Conclusion and Prospect | 第33-37页 |
| Chapter 2 Subject Design and Research Content | 第37-41页 |
| 2.1 Introduction | 第37页 |
| 2.2 Hypervalent Iodine Reagents-mediated Cascade Reaction of Kito-amide Derivatives | 第37-39页 |
| 2.3 Project Design and Feasibility Analysis | 第39-40页 |
| 2.4 Preliminary Research Results | 第40页 |
| 2.5 Research Contents | 第40-41页 |
| Chapter 3 Research Results and Discussion | 第41-49页 |
| 3.1 Introduction | 第41页 |
| 3.2 Discovery of Hypervalent Iodine Reagents Mediated Oxidative Tandem Reaction and Confirmation of Product Structure | 第41-42页 |
| 3.3 Optimization and Discussion of Reaction Conditions | 第42-43页 |
| 3.4 Investigation of the Scope of Substrate Application | 第43-44页 |
| 3.5 Discussion on the Applicability of the Method | 第44-46页 |
| 3.6 Reaction Mechanism | 第46-48页 |
| 3.7 Summary | 第48-49页 |
| Chapter 4 Conclusion | 第49-51页 |
| Chapter 5 Experiment Section | 第51-69页 |
| 5.1 General Information | 第51页 |
| 5.2 Experimental Section | 第51-54页 |
| 5.2.1 Preparation of Substrates | 第51-53页 |
| 5.2.2 Preparation of Compounds 153 | 第53页 |
| 5.2.3 Preparation of Intermediate 158 | 第53-54页 |
| 5.3 Spectral Data of Substrates and Products | 第54-69页 |
| 5.3.1 Spectral Data of Substrates | 第54-69页 |
| References | 第69-79页 |
| Notes on Publications and Participation in Scientific Research | 第79-81页 |
| Appendix 1:Copies of ~1H-NMR and ~(13)C-NMR Spectra | 第81-117页 |
| Appendix 2:X-ray Structure and Data of 153m | 第117-127页 |
| Acknowledgement | 第127页 |
