| Abstract | 第5页 |
| 摘要 | 第6-22页 |
| List of Abbreviations | 第22-24页 |
| 1 Introduction | 第24-53页 |
| 1.1 Organic Fluorescent Materials | 第24-26页 |
| 1.1.1 Basic Principle of Fluorescence in Organic Materials | 第25-26页 |
| 1.2 Aggregation caused quenching feature (ACQ) | 第26-28页 |
| 1.3 Aggregation-induced emission feature (AIE) | 第28-44页 |
| 1.3.1 AIE Working Mechanism | 第30-34页 |
| 1.3.2 AIE-gen systems | 第34-38页 |
| 1.3.3 Technological Applications | 第38-44页 |
| 1.4 Stimuli Responsive Fluorescent Organic Gel | 第44-50页 |
| 1.4.1 Metal Organic supramolecular Gel | 第46-47页 |
| 1.4.2 Applications | 第47-50页 |
| 1.5 Thesis Objectives | 第50-53页 |
| 2 Development of Tunable Fluorophores via Isobutylene bis-naphthylamide Cores:As a New AIE-Active Family | 第53-72页 |
| 2.1 Introduction | 第53-55页 |
| 2.2 Experimental Section | 第55-57页 |
| 2.2.1 Material and instruments | 第55页 |
| 2.2.2 Synthesis of fluorophore 1-AB | 第55-56页 |
| 2.2.3 Synthesis of fluorophore 2-AN | 第56页 |
| 2.2.4 Synthesis of fluorophore 2-AA | 第56-57页 |
| 2.2.5 AIE experiments | 第57页 |
| 2.2.6 Theoretical calculations (DFT/ TD-DFT) methods | 第57页 |
| 2.3 Results and Discussion | 第57-71页 |
| 2.3.1 Single crystal analysis and supramolecular interactions | 第58-61页 |
| 2.3.2 Aggregation induced emission (AIE) property | 第61-65页 |
| 2.3.3 Theoretical calculations(DFT/TD-DFT) | 第65-71页 |
| 2.4 Summary | 第71-72页 |
| 3 Two New Fluorescent Zn~(2+) Sensors Exhibiting Different Sensing Modes withSubtle Structural Changes | 第72-89页 |
| 3.1 Introduction | 第72-73页 |
| 3.2 Experimental Section | 第73-78页 |
| 3.2.1 Instruments and reagents | 第73-74页 |
| 3.2.2 Binding constants for receptors HL-1 and HL-2 towards Zn~(2+) | 第74-75页 |
| 3.2.3 Detection Limit of receptors HL-1 and HL-2 for Zn~(2+) | 第75页 |
| 3.2.4 Synthesis of compound HL-1 | 第75-76页 |
| 3.2.5 Preparation of HL-1-Zn | 第76页 |
| 3.2.6 Synthesis of compound HL-2 | 第76页 |
| 3.2.7 Synthesis of compound HL | 第76-77页 |
| 3.2.8 Preparation of sample solution for analysis | 第77-78页 |
| 3.3 Results and Discussion | 第78-88页 |
| 3.3.1 Fluorescence spectroscopic studies of HL-1 and HL-2 in the presenceof various metal ions | 第78-81页 |
| 3.3.2 Absorption spectroscopic studies | 第81-82页 |
| 3.3.3 Partial ~1H NMR of HL-1 and HL-2 with Zn~(2+) | 第82-85页 |
| 3.3.4 ESI-MS analysis | 第85页 |
| 3.3.5 Signalling mechanisms of Zn~(2+) ion with HL-2 and HL-1 | 第85-88页 |
| 3.4 Summary | 第88-89页 |
| 4 Aggregation-Induced Emission (AIE) Fluorophore Exhibits a Highly RatiometricFluorescent Response to Zn~(2+) in vitro and in Human Liver Cancer Cells | 第89-114页 |
| 4.1 Introduction | 第89-90页 |
| 4.2 Experimental section | 第90-94页 |
| 4.2.1 Materials and instrumentation | 第90-91页 |
| 4.2.2 UV-Vis and fluorescence measurements | 第91页 |
| 4.2.3 Calculation of binding constants for 8AQ towards Zn~(2+) | 第91页 |
| 4.2.4 Detection limit of 8AQ towards Zn~(2+) | 第91-92页 |
| 4.2.5 Theoretical method (DFT and TD-DFT) | 第92页 |
| 4.2.6 Fluorescence imaging in living Cells | 第92页 |
| 4.2.7 MTT assay | 第92-93页 |
| 4.2.8 Synthesis of fluorophore 8AQ | 第93页 |
| 4.2.9 Synthesis of compound 8WB | 第93-94页 |
| 4.3 Results and Discussion | 第94-113页 |
| 4.3.1 Single crystal structure and supramolecular interactions | 第95-98页 |
| 4.3.2 Aggregation-induced emission (AIE) behaviour of fluorophore 8AQ | 第98-99页 |
| 4.3.3 Absorption spectroscopic studies of 8AQ with various metal ions | 第99-100页 |
| 4.3.4 Fluorescence response of fluorophore 8AQ with various metal ions | 第100-102页 |
| 4.3.5 ~1H NMR titration of fluorophore 8AQ with Zn~(2+) to study the bindingmode and composition of metal complex 8AQ-Zn | 第102-104页 |
| 4.3.6 ESI-MS experiment | 第104-105页 |
| 4.3.7 Theoretical calculation (DFT/TD-DFT) methods | 第105-109页 |
| 4.3.8 Signalling mechanism of fluorophore 8AQ with Zn~(2+) | 第109-110页 |
| 4.3.9 Biological cell-permeability of 8AQ and intracellular ratiometicfluorescence response towards Zn~(2+) | 第110-111页 |
| 4.3.10 MTT assay | 第111-113页 |
| 4.4 Summary | 第113-114页 |
| 5 A Novel Smart Supramolecular Organic Gelator Exhibiting Dual-channelResponsive Sensing Behaviours towards Fluoride ion via Gel-Gel State | 第114-132页 |
| 5.1 Introduction | 第114-116页 |
| 5.2 Experimental Section | 第116-119页 |
| 5.2.1 Materials and reagents | 第116页 |
| 5.2.2 Gelation test | 第116页 |
| 5.2.3 Calculation of binding constants for metallo-gel OG-Zn towards F~- | 第116-117页 |
| 5.2.4 Detection limit of supramolecular metal organic gel OG-Zn for F~- | 第117页 |
| 5.2.5 Synthesis of gelator G-16 | 第117-119页 |
| 5.3 Results and Discussion | 第119-131页 |
| 5.3.1 Gelation properties of G-16 | 第119-120页 |
| 5.3.2 Fluorescence response of OG towards metal ions | 第120-121页 |
| 5.3.3 Fluorescence response of OG and OG-Zn towards anions | 第121-124页 |
| 5.3.4 Self-assembly mechanism in OG and OG-Zn | 第124-127页 |
| 5.3.5 Stimuli responsive mechanism of OG and OG-Zn towards F~- ion | 第127-129页 |
| 5.3.6 Morphological studies of OG, OG-Zn, OG-Zn-F and OG-F | 第129-130页 |
| 5.3.7 Rheological studies | 第130-131页 |
| 5.4 Summary | 第131-132页 |
| 6 Conclusion | 第132-134页 |
| Innovation Points and Future Horizons | 第134-136页 |
| Innovation Points | 第134-135页 |
| Future Horizons | 第135-136页 |
| References | 第136-155页 |
| Published Academic Articles during PhD Period | 第155-156页 |
| Supplementary Materials | 第156-165页 |
| Acknowledgement | 第165-167页 |
| About the Author | 第167-169页 |
