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超级蒙卡核模拟软件系统SuperMC在近距离放疗和硼中子俘获治疗中的测试和应用

ABSTRACT第5-6页
Nomenclature第13-15页
Chapter 1 Introduction第15-31页
    1.1 Overview of radiotherapy第15-16页
    1.2 Brachytherapy第16-23页
        1.2.1 Radioactive isotopes used for brachytherapy第17-18页
        1.2.2 Source Construction第18-19页
        1.2.3 Remote Control Afterloading第19-23页
    1.3 Boron Neutron Capture Therapy (BNCT)第23-30页
        1.3.1 Neutron Sources第25-28页
        1.3.2 Dose Components第28-30页
    1.4 Aims of this study第30页
    1.5 Thesis structure and outline第30-31页
Chapter 2 Monte Carlo Methods in Radiotherapy第31-49页
    2 .1 Fundamentals of Monte Carlo Methods第31-36页
        2.1.1 Random Number Generator第31-32页
        2.1.2 Inverse Transformation Method第32-34页
        2.1.3 Russian Roulette第34页
        2.1.4 Rejection Method第34-35页
        2.1.5 Numerical Integration第35-36页
    2.2 Monte Carlo Simulation of Particle Transport第36-42页
        2.2.1 Photon Transport第36-39页
        2.2.2 Electron Transport第39-41页
        2.2.3 Neutron Transport第41-42页
    2.3 Overview of Monte Carlo codes in medical physics第42-43页
    2.4 Introduction of SuperMC第43-49页
        2.4.1 Functions of SuperMC第43-47页
        2.4.2 Validation and Verification of SuperMC第47-49页
Chapter 3 Verification of SuperMC for Brachytherapy第49-63页
    3.1 Source specification and Dosimetry第49-54页
        3.1.1 Traditional Methods第49-51页
        3.1.2 AAPM Task Group 43 Formalism第51-54页
    3.2 Modeling of Brachytherapy Source第54-57页
        3.2.1 Source Specification第54页
        3.2.2 Monte Carlo Simulation第54-57页
    3.3 Results and Discussions第57-61页
        3.3.1 Fluence Spectrum of ~(192)Ir Source Model第57页
        3.3.2 Air Kerma Strength and Dose Rate Constant第57-59页
        3.3.3 Radial Dose and Anisotropy Function第59-61页
    3.4 Conclusion第61-63页
Chapter 4 Application of SuperMC for BNCT第63-77页
    4.1 Neutron source characterization第63-64页
    4.2 BSA design and optimization第64-71页
        4.2.1 Neutron Amplifier第65页
        4.2.2 Moderator第65-66页
        4.2.3 Reflector第66-69页
        4.2.4 Thermal Neutron Filter第69页
        4.2.5 Gamma Shield and Collimator第69-71页
    4.3 Estimation of Absorbed Dose in Air第71页
    4.4 Estimation of Absorbed Dose in Head Phantom第71-75页
        4.4.1 Tissue Composition第71-72页
        4.4.2 Fluence to Kerma Conversion Factors第72-73页
        4.4.3 Dose Distributions第73-75页
    4.5 Discussion and Conclusion第75-77页
Chapter 5 Conclusion and Future Work第77-81页
    5.1 Summary and conclusions第77-78页
    5.2 Recommendations for future work第78-81页
References第81-89页
Appendix A Fluence to kerma conversion factors for neutrons,pho-ton mass attenuation coefficients第89-97页
    A.0.1 Fluence to kerma conversion factors for neutrons,taken from InternationalCommission on Radiation Units and Measurements(ICRU) Report No.63[114]第89-95页
    A.0.2 Photon mass attenuation coefficients in tissue, taken from Seltzer et al.[115]第95-97页
Acknowledgement第97-99页
Publications and Research Achievements第99页

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