| 摘要 | 第4-8页 |
| abstract | 第8页 |
| Chapter1.Introduction | 第11-29页 |
| 1.1 Natural product chemistry | 第15-18页 |
| 1.2 Previous studies about Atraphaxis spinosa | 第18-25页 |
| 1.2.1 General characters of the genus Atraphaxis | 第18页 |
| 1.2.2 Chemical review of the genus Atraphaxis | 第18-25页 |
| 1.3 Previous studies about Camphorosma lessingii Litv | 第25-29页 |
| 1.3.1 General characters of the genus Camphorosma | 第25-26页 |
| 1.3.2 Chemical review of the genus Camphorosma | 第26-27页 |
| 1.3.3 Biological review of the genus Camphorosma | 第27页 |
| 1.3.4 General characteristics of OATs | 第27-29页 |
| Chapter2.The research process of Natural product chemistry | 第29-35页 |
| 2.1 The general research process | 第29页 |
| 2.2 How to find the target compounds | 第29-31页 |
| 2.3 HPLC mobile phase conditions during the separation | 第31-32页 |
| 2.4 The selection of chromatographic column | 第32-33页 |
| 2.5 The analysis of chromatogram peak | 第33-35页 |
| Chapter3.Material and methods | 第35-51页 |
| 3.1 Materials and methods of Atraphaxis spinosa | 第35-40页 |
| 3.1.1 Plant material | 第35页 |
| 3.1.2 General experimental procedures of Atraphaxis spinosa | 第35-36页 |
| 3.1.3 Solvents | 第36页 |
| 3.1.4 Extraction and isolation of Atraphaxis spinosa | 第36-40页 |
| 3.2 Materials and methods of Camphorosma lessingii Litv | 第40-46页 |
| 3.2.1 Plant material | 第40页 |
| 3.2.2 General experimental procedures of Camphorosma lessingii | 第40-41页 |
| 3.2.3 Extraction and solvent partitioning of Camphorosma lessingii | 第41-42页 |
| 3.2.4 Chromatography of the DCM fraction of Camphorosma lessingii | 第42-44页 |
| 3.2.5 Biological screening of Camphorosma lessingii Litv | 第44-45页 |
| 3.2.6 Inhibition of OAT1-and OAT3-mediated6-CF transport using compounds isolated from Camphorosma lessingii | 第45-46页 |
| 3.3 Methods used for Atraphaxis spinosa and Camphorosma lessingii | 第46-51页 |
| 3.3.1 Chromatographic methods | 第46-48页 |
| 3.3.2 Structure elucidation | 第48-49页 |
| 3.3.3 Analysis of the flavonoids | 第49-51页 |
| Chapter4.Results and Discussion | 第51-77页 |
| 4.1 Isolation and Identification of compounds from Atraphaxis spinosa | 第51-60页 |
| 4.2 Chemotaxonomic significance of compounds from Atraphaxis spinosa | 第60-61页 |
| 4.3 Spectroscopic data for metabolites of Atraphaxis spinosa | 第61-64页 |
| 4.4 Isolation and Identification of compounds from Camphorosma lessingii | 第64-71页 |
| 4.5 Inhibitory effect of the DCM extracts of Camphorosma lessingii Litv | 第71-72页 |
| 4.6 Spectroscopic data for metabolites of Camphorosma lessingii Litv | 第72-77页 |
| Chapter5.Conclusion | 第77-79页 |
| References | 第79-87页 |
| Glossary of Abbreviations | 第87-88页 |
| Appendix | 第88-162页 |
| Notes on publications and participation in scientific research | 第162-163页 |
| Acknowledgement | 第163页 |
