| Abstract | 第5-8页 |
| 摘要 | 第9-15页 |
| Preface | 第15-20页 |
| Chapter One Introduction Association between Air Pollution and Cardiovascular Disease | 第20-26页 |
| 1.1 Background | 第20-21页 |
| 1.2 Global Burden of Air Pollution Affecting Human Health | 第21-22页 |
| 1.3 Air Pollution in China | 第22-23页 |
| 1.4 Epidemiology of PM_(2.5) associated with the risk of CVD | 第23-24页 |
| 1.5 Study Significance | 第24-25页 |
| 1.6 Aims of this Study | 第25-26页 |
| Chapter Two Literature Review Cardiovascular Disease Associated with the Exposure of Particulate Matter and Trimethylamine N-oxide | 第26-38页 |
| 2.1 Introduction | 第26页 |
| 2.2 Constituents of Air Pollution | 第26-27页 |
| 2.3 Source of PM_(2.5) | 第27页 |
| 2.4 PM research in cities of the world | 第27-28页 |
| 2.5 Particulate matter standards | 第28-29页 |
| 2.6 Circulatory Biomarkers | 第29-30页 |
| 2.7 Mechanisms of PM_(2.5) and TMAO associated with CVD | 第30-36页 |
| 2.7.1 How Particulate Matter Enters the Body | 第30-31页 |
| 2.7.2 Pulmonary inflammation and Oxidative Study | 第31-32页 |
| 2.7.3 PM_(2.5) Associated with Blood Pressure and Risk of Developing Hypertension | 第32-33页 |
| 2.7.4 Coagulation and Thrombosis | 第33页 |
| 2.7.5 Atherosclerosis and Vascular Dysfunction | 第33-34页 |
| 2.7.6 Role of TMAO in human organs | 第34-35页 |
| 2.7.7 Health Effects by Particulate Matters | 第35-36页 |
| 2.8 Environmental effects by Particulate Matters | 第36-38页 |
| 2.8.1 Reduction in visibility | 第36页 |
| 2.8.2 Environmental damages | 第36页 |
| 2.8.3 Aesthetic damages | 第36-37页 |
| 2.8.4 Climate change | 第37-38页 |
| Chapter Three Descriptive Analysis of PM_(2.5) Associated with Blood Pressure And TMAO Level | 第38-48页 |
| 3.1 Introduction | 第38页 |
| 3.2 Methods and Materials | 第38-39页 |
| 3.2.1 Study Population and Design | 第38页 |
| 3.2.2 Measurement of Blood Pressure | 第38-39页 |
| 3.2.3 Measurement of TMAO | 第39页 |
| 3.2.4 Statistical Analysis | 第39页 |
| 3.3 Results | 第39-43页 |
| 3.3.1 Overview of the Studies Included in The Thesis | 第39-40页 |
| 3.3.2 Association between PM_(2.5) and Blood Pressure | 第40-42页 |
| 3.3.3 Association between PM_(2.5) and TMAO | 第42-43页 |
| 3.4 Discussion | 第43-47页 |
| 3.5 Conclusion | 第47-48页 |
| References | 第48-66页 |
| Biography | 第66-67页 |
| Acknowledgement | 第67-68页 |
