| 摘要 | 第3-6页 |
| Abstract | 第6-8页 |
| List of Abbreviations | 第11-12页 |
| Part Ⅰ Introduction | 第12-18页 |
| 1.1 The regulation of hypothalamus-pituitary-adrenal axis (HPA) during development | 第12页 |
| 1.2 A special development pattern of hypothalamus-pituitary-adrenal axis (HPA): stress hypo-responsive period (SHRP) | 第12-13页 |
| 1.3 Maternal regulation on hypothalamus-pituitary-adrenal axis (HPA) | 第13-15页 |
| 1.4 Paternal care on the development of offspring | 第15-16页 |
| 1.5 Arginine vasopressin (AVP) and oxytocin (OT) in regulating behavior and emotion | 第16-17页 |
| 1.6 The model animal:mandarin vole (Microtus mandarinus) | 第17-18页 |
| Part Ⅱ Materials and methods | 第18-22页 |
| 2.1 Subjects | 第18页 |
| 2.2 Experimental design | 第18-19页 |
| 2.3 Testing procedure | 第19-21页 |
| 2.4 Statistical analyses | 第21-22页 |
| Part Ⅲ Results | 第22-34页 |
| 3.1 Test the SHRP in mandarin voles | 第22-27页 |
| 3.1.1 Corticosterone (CORT) test | 第22-23页 |
| 3.1.2 Pituitary adrenocorticotropin (ACTH) test | 第23-24页 |
| 3.1.3 The number of AVP-immunoreactive neurons | 第24-25页 |
| 3.1.4 The number of OT-immunoreactive neurons | 第25-27页 |
| 3.2 The effects of paternal deprivation on the stress response | 第27-34页 |
| 3.2.1 Corticosterone (CORT) test | 第27-28页 |
| 3.2.2 Pituitary adrenocorticotropin(ACTH) test | 第28-29页 |
| 3.2.3 The number of AVP-immunoreactive neurons | 第29-31页 |
| 3.2.4 The number of OT-immunoreactive neurons | 第31-34页 |
| Part Ⅳ Discussion | 第34-40页 |
| 4.1 Part 1:development of the HPA axis | 第34-37页 |
| 4.1.1 HPA axis response to stress in early postnatal day | 第34-36页 |
| 4.1.2 AVP and OT response to stress in early development of mandarin vole | 第36-37页 |
| 4.2 Part two:effects of paternal deprivation on stress responses | 第37-40页 |
| 4.2.1 The effects of paternal deprivation on responses of HPA axis in and outside the SHRP | 第37-38页 |
| 4.2.2 AVP and OT in regulating the HPA axis after paternal deprivation | 第38-40页 |
| Conclusions | 第40-42页 |
| References | 第42-54页 |
| Plates | 第54-60页 |
| Acknowledgments | 第60页 |
