首页--医药、卫生论文--眼科学论文--眼损伤与异物论文

维甲酸对碱烧伤引起的角膜新血管生成的作用及机制研究

中文摘要第6-9页
ABSTRACT第9-11页
Abbreviations 缩略语第14-16页
1 INTRODUTION第16-21页
2. MATERIALS AND METHODS第21-27页
    2.1 Materials第21-22页
        2.1.1 Cell culture第21页
        2.1.2 Animals第21页
        2.1.3 Antiboies第21-22页
    2.2 Methods第22-27页
        2.2.1 Alkali-burn Corneal Injury and retinoic acid Treatment第22页
        2.2.2 Clinical Assessment of Corneal NV第22-23页
        2.2.3 Western blot analysis and ELISA第23页
        2.2.4 Quantitative real-time PCR for TSP-1第23-24页
        2.2.5 Proliferation assay第24-25页
        2.2.6 Migration assay第25页
        2.2.7 Tube formation assay第25-26页
        2.2.8 Flow cytometry第26页
        2.2.10 Statistical analysis第26-27页
3. RESULTS第27-51页
    3.1 Inhibitory effect of RA on corneal NV第27-30页
    3.2 Effect of RA on expression of angiogenic and anti-angiogenic factors第30-36页
        3.2.1 Effect of RA on expression of anti-angiogenic factor TSP-1 in alkali-burninduced CNV in vivo第30-33页
        3.2.2 Effect of RA on expression of angiogenic factor VEGF in alkali-burn inducedCNV in vivo第33-36页
    3.3 Effect of RA on proliferation, migration and differentiation (tube formation)of microvascular endothelial cells in vitro第36-42页
        3.3.1 Effect of RA on proliferationof HDMEC in vitro第36-38页
        3.3.2 Effect of RA on migration of HDMEC in vitro第38-40页
        3.3.3 Effect of RA on differentiation of HDMEC in vitro第40-42页
    3.4 Effects of RA on the expression of TSP-1 in HDMEC第42-45页
    3.5 Effects of RA on the secretion of TSP-1 from HDMEC第45-47页
    3.6 Effects of RA on HDMEC apoptosis第47-49页
    3.7 Regulation of caspase-3 and Bcl-2 expression by RA第49-51页
4. DISCUSSION第51-56页
5. CONCLUSIONS第56-57页
REFERENCES第57-65页
综述第65-97页
    参考文献第85-97页
致谢第97页

论文共97页,点击 下载论文
上一篇:基于网络的分布式机群并行仿真平台开发
下一篇:基于“三权分立”思想的风景名胜区管理体制创新研究