| Abstract | 第6-8页 |
| 1 Introduction | 第9-21页 |
| 1.1 Effect of Se on immune organs | 第9-10页 |
| 1.2 Selenoprotein function and expression | 第10-13页 |
| 1.3 Cytokines function and expression | 第13-15页 |
| 1.4 Hsps function and expression | 第15-17页 |
| 1.5 Autophagy function and expression | 第17-20页 |
| 1.6 Objectives of Research | 第20-21页 |
| 2 Materials and Methods | 第21-29页 |
| 2.1 Chicken Diet | 第21页 |
| 2.2 Determination of mRNAs levels by Quantitative Real-Time PCR | 第21-22页 |
| 2.3 Western blot analysis | 第22页 |
| 2.4 Determination of Immune Function | 第22-23页 |
| 2.5 Determination of Ultra structure | 第23页 |
| 2.6 Statistical Analysis | 第23-29页 |
| 3 Results | 第29-65页 |
| 3.1 Result of selenoproteins mRNA level in chicken spleen | 第29-31页 |
| 3.2 Result of selenoproteins mRNA level in chicken bursa of Faricius | 第31-32页 |
| 3.3 Result of selenoproteins mRNA level in chicken thymus | 第32-34页 |
| 3.4 Result of cytokines in chicken spleen | 第34-37页 |
| 3.5 Result of cytokines in chicken bursa of Fabricius | 第37-40页 |
| 3.6 Result of cytokines in chicken thymus | 第40-43页 |
| 3.7 Result of Hsp mRNA levels in chicken spleen | 第43-45页 |
| 3.8 Result of Hsps mRNA levels in the chicken bursa of Fabricius | 第45-47页 |
| 3.9 Result of Hsp mRNA levels in chicken thymus | 第47-49页 |
| 3.10 Result of Hsps protein levels in chicken spleen | 第49-50页 |
| 3.11 Result of Hsps protein levels in the chicken bursa of Fabricius | 第50-52页 |
| 3.12 Result of Hsps protein levels in chicken thymus | 第52-53页 |
| 3.13 Result of autophagy genes mRNA levels in chicken spleen | 第53-55页 |
| 3.14 Result of autophagy genes mRNA levels in chicken bursa of Fabricius | 第55-57页 |
| 3.15 Effect of Se deficiency on autophagy genes mRNA levels in chicken thymus | 第57-59页 |
| 3.16 Result of autophagy genes protein level in chicken spleen | 第59-60页 |
| 3.17 Result of autophagy genes protein level in chicken bursa of Fabricius | 第60-62页 |
| 3.18 Result of autophagy genes protein level in chicken thymus | 第62-63页 |
| 3.19 Result of ultrastrcuture expression in spleen, bursa of Fabricious and thymus of chicken | 第63-65页 |
| 4 Discussion | 第65-74页 |
| 4.1 Effect of dietary Se on selenoproteins mRNA level in chicken immune organs | 第65-66页 |
| 4.2 Effect of dietary Se on cytokines expression level in chicken immune organs | 第66-69页 |
| 4.3 Effect of dietary Se on Hsps expression level in chicken immune organs | 第69-71页 |
| 4.4 Effect of dietary Se on autophagy related genes level in chicken immune organs | 第71-73页 |
| 4.5 Effect of dietary Se on ultrastructure of immune organs of chicken | 第73-74页 |
| 5 Conclusions | 第74-76页 |
| Acknowledgements | 第76-77页 |
| References | 第77-92页 |
| List of Abbreviation | 第92-94页 |
| Peer Reviewed Publications | 第94页 |
