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对于负载天然活性成分的抗菌和抗利仕曼虫金属材料的合成与功能化研究

学位论文数据集第4-8页
ABSTRACT第8-10页
摘要第11-26页
Chapter 1 Exordium第26-56页
    1. Introduction第26-56页
        1.1. Antimicrobial activity of metal nanoparticles第29-31页
        1.2. Leishmaniasis第31-34页
            1.2.1. Life cycle (Leishmania)第33-34页
            1.2.2. Available antileishmanial drugs第34页
        1.3. Green synthesis of metal nanoparticles第34-35页
        1.4. Silver (Ag) and gold (Au) nanoparticles第35-37页
        1.5. Copper and zinc oxide nanoparticles第37-38页
        1.6. Antileishmanial activity of metal nanoparticles第38-43页
        1.7. Antileishmanial activity of biogenic selenium nanoparticles第43-44页
        1.8. Antileishmanial action of biogenic Ag and Au nanoparticles第44-48页
        1.9. Mechanisms and molecular targets in leishmania第48-53页
        1.10. Cytotoxicity of biogenic metal nanoparticles第53-56页
Chapter 2第56-64页
    2. Materials and methods第56-64页
        2.1. Materials and chemicals第56页
        2.2. Preparation of plant extracts第56页
        2.3. Phytosynthesis of Ag nanoparticles第56-57页
        2.4. Phytosynthesis of gold nanoparticles第57页
        2.5. Amphotericin B conjugated AgNPs第57-58页
        2.6. Preparation of chitosan functionalized nanoparticles第58页
        2.7. Characterization第58-59页
        2.8. Biological applications第59-62页
            2.8.1. Antibacterial efficacy of Ag and AuNPs第59页
            2.8.2. Antifungal activity of Ag and AuNPs第59-60页
            2.8.3. Antileishmanial activity第60页
            2.8.4. Investigation of reactive oxygen species (ROS)第60-61页
            2.8.5. Bacterial ultra-structure第61页
            2.8.6. Membrane damage第61页
            2.8.7. Propidium iodide assay第61-62页
        2.9. Catalytic applications第62-64页
            2.9.1. Photocatalytic reduction of methylene blue第62页
            2.9.2. 4-nitrophenol reduction第62-64页
Chapter 3 Silver and gold nanoparticles from Sargentodoxa cuneata: synthesis, characterization and antileishmanial activities第64-84页
    3.1. UV-Vis spectroscopy第64-68页
    3.2. XRD第68-70页
    3.3. EDX spectral analysis第70-71页
    3.4. High-resolution TEM(HRTEM)study第71-73页
    3.5. FTIR analysis第73-74页
    3.6. Antibacterial activity第74-80页
    3.7. Antileishmanial activity第80-83页
    3.8. Summary第83-84页
Chapter 4 Isatis tinctoria mediated synthesis of amphotericin B-bound silver nanoparticles with enhanced photo-induced antileishmanial activity: A novel green approach第84-94页
    4.1. Synthesis of AgNPs第84-85页
    4.2. Particles size and morphology第85-87页
    4.3. Zeta potential第87-88页
    4.4. XRD and Energy dispersive X-ray (EDX)第88-89页
    4.5. FTIR第89-90页
    4.6. Antileishmanial efficacy第90-92页
    4.7. Summary第92-94页
Chapter 5 The effects of bacteria-nanoparticles interface on the antibacterial activity of green synthesized silver nanoparticles第94-108页
    5.1. UV-Vis spectroscopy第94-95页
    5.2. X-Ray Diffraction and EDX profiling第95-96页
    5.3. Particles size and shapes第96-97页
    5.4. Zeta value of the prepared nanoparticles第97-98页
    5.6. FTIR第98-100页
    5.7. Antibacterial activity第100-102页
    5.8. Measurment of cell constituents release第102-104页
    5.9. Propidium iodide assay第104-105页
    5.10. Determination intracellular of reactive oxygen species第105-106页
    5.11. Summary第106-108页
Chapter 6 Size-dependent catalytic activities of green synthesized gold nanoparticles and electrocatalytic oxidation of catechol on gold nanoparticles modified electrode第108-124页
    6.1. AuNPs synthesis第108-110页
    6.2. XRD of AuNPs第110页
    6.3. TEM study of AuNPs第110-112页
    6.4. FTIR第112-113页
    6.5. Photocatalytic activity第113-117页
    6.6. Reduction of nitrophenol第117-120页
    6.7. Electrochemical behavior of AuNPs modified GC electrode第120-122页
    6.8. Summary第122-124页
Chapter 7 Conclusion第124-128页
Acknowledgements第128-130页
Future plan第130-132页
List of publications第132-136页
Aftab Ahmad (Author)第136-138页
PROF.QIPENG YUAN第138-142页
Professor Dr. Yun Wei(Research Supervisor)第142-144页
References第144-158页
附件第158-159页

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