| ACKNOWLEDGEMENT | 第6-8页 |
| ABBREVIATION | 第8-10页 |
| ABSTRACT | 第10页 |
| Introduction | 第11页 |
| Risk factors of Atrial Fibrillation | 第11-12页 |
| Prevalence of Atrial Fibrillation | 第12页 |
| Contraindication to Warfarin Therapy | 第12-13页 |
| Contraindication to New Oral Anticoagulation Therapy | 第13-14页 |
| Stroke Risk Assessment in Patients with Non Valvular Atrial Fibrillation | 第14页 |
| Therapeutic Strategies to Prevent Stroke in Atrial Fibrillation Patients | 第14-17页 |
| Catheter Ablation | 第17页 |
| Percutaneous Transcatheter Closure of the Left atrial appendage | 第17-18页 |
| WATCHMAN device Description | 第18-19页 |
| Implantation of the WATCHMAN Device | 第19-20页 |
| Trials and studies looking at efficacy and safety of Watchman device | 第20-26页 |
| Current evidence derived from surgical LAA occlusion | 第26-31页 |
| Conclusion | 第31-32页 |
| Disclosure Statement | 第32-33页 |
| References | 第33-40页 |
