| ABSTRACT | 第8-10页 |
| Chinese abstract | 第12-15页 |
| INTRODUCTION | 第15-17页 |
| MATERIALS AND METHODS | 第17-22页 |
| Extraction and isolation of crude polysaccharides | 第17-18页 |
| Analysis of monosaccharide composition | 第18页 |
| Animal model | 第18-19页 |
| Induction of colitis | 第19页 |
| Histological score assessment of colitis | 第19页 |
| Immunohistochemistry | 第19-20页 |
| Alcian blue and nuclear fast staining | 第20页 |
| Myeloperoxidase activity | 第20-21页 |
| Western blotting analysis | 第21页 |
| Statistical analysis | 第21-22页 |
| RESULTS | 第22-33页 |
| Extraction and characterization of polysaccharide from ABM | 第22-25页 |
| ABM polysaccharide inhibited DSS-induced intestinal colitis | 第25-27页 |
| Polysaccharide isolated from Agaricus blazei Murill stimulated the production of goblet cell inmice colonic mucosa | 第27-28页 |
| ABM polysaccharide enhances colonic mucosal barrier function in colitis via MUC2 and TFF3production | 第28-31页 |
| ABM polysaccharide inhibited myeloperoxidase activity in mice with DSS-induced colitis | 第31-32页 |
| Polysaccharide extracted from ABM induced HGF activation, inhibited Cox-2 and NF-Kbexpression | 第32-33页 |
| DISCUSSION | 第33-37页 |
| CONCLUSION | 第37-38页 |
| REFERENCES | 第38-42页 |
| LITERATURE REVIEW ROLE OF POLYSACCHARIDE AS PREBIOTIC IN INFLAMMATORY BOWELDISEASE | 第42-56页 |
| INTRODUCTION | 第42-44页 |
| The prevalence of inflammatory bowel disease in the world | 第44-46页 |
| Health benefits of Agaricus blazei Murill in gastrointestinal inflammation | 第46-47页 |
| Role of prebiotics in intestinal barrier function | 第47-48页 |
| Beneficial effect of prebiotic | 第48-50页 |
| Effects of dietary fiber on inflammatory bowel disease | 第50-51页 |
| Mechanism of action of polysaccharide in the treatment or prevention of IBD | 第51-53页 |
| REFERENCES | 第53-56页 |
| ACKNOWLEDGEMENTS | 第56页 |
