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Copper-Catalyzed Aminolysis of Beta, Beta-Dialkylthio Carbonyls with Ammonia: Synthesis of Enaminones with a Free Beta-Amino Group

Table of content第4-6页
Acknowledgements第6-7页
Abstract第7-8页
Chapiter-1- Introduction第9-38页
    1- Background studies on importance of enaminones第9-26页
        1-1- Brief History of enaminones第9-10页
        1-2- Enaminones in heterocyclic synthesis第10-17页
        1-3- Enaminones:Reactivity and use as versatile intermediates in organic synthesis第17-23页
        1-4- Importance of enaminones in pharmaceutical chemistry第23-26页
        1-5- Importance of enaminones containing free amino-group第26页
    2- Background studies on the synthesis of enaminones第26-32页
        2-1- Related work on the synthesis of enaminones第26-32页
        2-2- Related work on the synthesis of enaminones with free amino group第32页
    3- Importance of this research第32-35页
        3-1- Statement of the problem第34-35页
    4- Beta,beta-Dialkylthio Carbonyls as intermediaries in organic chemistry第35-37页
        4-1- Literature review on the synthesis of beta,beta-Dialkylthio Carbonyls第35页
        4-2- Beta,beta-Dialkylthio Carbonyls as intermediates in organic chemistry第35-36页
        4-3- Reactivity of beta,beta-Dialkylthio Carbonyls第36-37页
            4-3-1- Reaction with amines第36页
            4-3-2- Reaction mechanism involving Beta,beta-Dialkylthiocarobonyl第36-37页
    5- Concluding remarks第37-38页
Chapter-2-Experimental part第38-43页
    2-1 Synthesis of Beta,beta-Dialkylthio Carbonyls第38页
        2-1-1-General procedure第38页
    2-2-Synthesis of enaminones第38-42页
        2-2-1-Optimization of the reaction condition第38页
        2-2-2-General procedure for the synthesis of enaminones第38-39页
        2-2-3-Experimental procedure第39-40页
            2-2-3-1 Presentation of results and discussions第39页
            2-2-3-2-Results for the synthesis of Beta,beta-Dialkythiocarbonyls第39-40页
                2-2-3-2-1 Discussions of results第40页
        2-2-4-Results for the synthesis of enaminones第40-42页
            2-2-4-1-Discussion of results on the synthesis of enaminones第41-42页
    2-3-Concluding remarks第42-43页
Chapter-3-Data analysis spectrum第43-65页
    3-1-Copies of ~1H NMR and ~(13)CNMR Spectrum data of starting materiel第43-56页
    3-2-copies of ~1H NMR and ~(13)CNMR Spectrum data of enaminones第56-65页
General conclusions and further works第65-66页
Publications第66页
References第66-67页

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