| Abbreviations | 第1-8页 |
| 摘要 | 第8-12页 |
| Abstract | 第12-17页 |
| Introduction | 第17-24页 |
| Chapter Ⅰ Activation of CRFR2 inhibits the growth of human small cell lung cancer cells | 第24-58页 |
| Part 1 Expression, localizations of CRF receptors in human SCLC tissues and cell lines | 第26-31页 |
| Part 2 Effect of CRFR2 on the proliferation and apoptosis of SCLC cells | 第31-38页 |
| Part 3 Relevant mechanisms of the inhibitory effect of CRFR2 in SCLC cells | 第38-50页 |
| Conclusion | 第50-58页 |
| Chapter Ⅱ UCN inhibits the tumor angiogenesis in human hepatocelluar carcinoma via CRFR | 第58-91页 |
| Part 1 Expression and localizations of CRF receptors in human HCC tissues and cell line | 第60-66页 |
| Part 2 UCN inhibits the tumor growth and angiogenesis in HCC via CRFR | 第66-78页 |
| Part 3 Activation of CRFR2 by UCN down-regulated the expression of vascular endothelial growth factor (VEGF) in vivo | 第78-86页 |
| Conclusion | 第86-91页 |
| Review: Corticotrophin-releasing factor family and its receptors: tumor therapeutic targets? | 第91-97页 |
| References | 第97-103页 |
| Novelty of the thesis | 第103-104页 |
| Publications | 第104页 |
| Honors and awards | 第104-105页 |
| Acknowledgement | 第105页 |
