| 提要 | 第1-8页 |
| Preface | 第8-14页 |
| 1 Introduction | 第14-70页 |
| ·Darwin and the origin of life | 第14-15页 |
| ·Hydrothermal systems as sites of life origin | 第15-26页 |
| ·Evidences convincing the hydrothermal origin of life | 第16-19页 |
| ·Evidences from impact bombardments | 第19-21页 |
| ·Evidences from life existing in deep sea hydrothermal vents | 第21-22页 |
| ·Life in deep sea hydrothermal vents | 第21页 |
| ·Independence from sunlight as energy source | 第21-22页 |
| ·Evidence from supercritical fluids | 第22-23页 |
| ·Evidence from classical synthesis and concept of compartmentation | 第23-26页 |
| ·Geochemistry of general ancient hydrothermal vents | 第26-30页 |
| ·Effects of impact bombardments on the geochemistry of hydrothermal vents and Hadean ocean | 第28-30页 |
| ·Life in extreme acidic hydrothermal environments | 第30-35页 |
| ·Generation and geochemistry of acidic vents | 第30-31页 |
| ·Life in acidic hydrothermal vents | 第31-32页 |
| ·Unfolding the mysterious life of acidophiles | 第32-34页 |
| ·Extreme acidic life in Rio Tinto | 第34-35页 |
| ·Classical prebiotic hydrothermal synthesis reactions | 第35-44页 |
| ·Hydrothermal reactions from sodium hydrogen carbonate to phenol | 第35-36页 |
| ·Hydrothermal biochemistry: from formaldehyde to oligopeptide | 第36-37页 |
| ·Autocatalytic synthesis of oligoglycine in a simulated submarine hydrothermal system | 第37-38页 |
| ·Condensation reactions and formation of amides, esters, and nitriles under hydrothermal conditions | 第38-39页 |
| ·Prebiotic hydrothermal synthesis of AcylGlycerols | 第39-40页 |
| ·Self assembly processes in the prebiotic environment | 第40-42页 |
| ·Phosphorylation of nucleotide molecules in hydrothermal environments | 第42页 |
| ·Nitrogen reduction under hydrothermal vent conditions: implications for the prebiotic synthesis of C-H-O-N compounds | 第42-44页 |
| ·Sources of phosphorus and prebiotic phosphorylation reactions | 第44-51页 |
| ·Sources of phosphorus | 第44-45页 |
| ·Apatite and prebiotic phosphorylations | 第45页 |
| ·Prebiotic phosphorylation reactions | 第45-48页 |
| ·Prebiotic formation of condensed phosphates | 第45-46页 |
| ·Volcanic production of polyphosphates and its relevance to prebiotic evolution | 第46-47页 |
| ·Production of potentially prebiotic condensed phosphates by phosphorus redox chemistry | 第47-48页 |
| ·Classical prebiotic synthesis reactions of biological phosphates | 第48-51页 |
| ·Phosphorylation of Adenosine with Trimetaphosphate under simulated prebiotic conditions | 第48页 |
| ·Cyanamide mediated prebiotic synthesis of glycerol phosphates | 第48页 |
| ·Urea-Inorganic phosphate mixtures as prebiotic phosphorylating agents | 第48-49页 |
| ·Phosphorylation of glyceric Acid in water by using Trimetaphosphate | 第49页 |
| ·Mineral induced formation of pentose -2,4-biphosphates | 第49-50页 |
| ·Prebiotic formation of ADP and ATP from AMP, calcium phosphates and cyanates in water | 第50-51页 |
| ·Prebiotic synthesis of phospholipids and self assembling vesicles | 第51-53页 |
| ·Synthesis of phospholipids and membranes in prebiotic conditions | 第51页 |
| ·Cyanide mediated synthesis of phosphatidic acids | 第51页 |
| ·Self assembly reactions | 第51-53页 |
| ·Prebiotic catalysis by minerals | 第53-59页 |
| ·Minerals as primordial womb | 第55-56页 |
| ·Minerals in acidic hydrothermal vents | 第56-59页 |
| ·The objectives and significance of present research | 第59-63页 |
| ·References | 第63-70页 |
| 2 Prebiotic hydrothermal synthesis and mineral catalysis of phosphate esters of glycerol and ethanolamine | 第70-93页 |
| ·Introduction | 第70-72页 |
| ·Experimental | 第72-79页 |
| ·Synthesis of glycerol phosphates | 第74-75页 |
| ·Effect of minerals on the synthesis of glycerol phosphates | 第75-77页 |
| ·Reaction selectivity by Perlite | 第77页 |
| ·Effect of pH on the synthesis of glycerol Phosphates | 第77-78页 |
| ·Effects of temperature & pressure on the synthesis of glycerol phosphates | 第78-79页 |
| ·Detection and analysis | 第79-85页 |
| ·Detection by classical method: the paper chromatography | 第79-82页 |
| ·Detection by LCMS | 第82-85页 |
| ·LCMS conditions | 第82-85页 |
| ·Prebiotic hydrothermal synthesis of Phosphoethanolamine | 第85-87页 |
| ·Detection of Phosphoethanolamine by Tandem Mass spectrometry | 第87页 |
| ·Some Interesting Side Reactions in our synthesis | 第87-89页 |
| ·Summary | 第89-91页 |
| ·References | 第91-93页 |
| 3 Prebiotic hydrothermal synthesis and mineral catalysis of glucose phosphates | 第93-107页 |
| ·Introduction | 第93-95页 |
| ·Experimental | 第95-97页 |
| ·Preparation of acidic prebiotic soup | 第95-96页 |
| ·Prebiotic hydrothermal synthesis of glucose phosphates | 第96-97页 |
| ·Detection and analysis | 第97-102页 |
| ·Detection by paper chromatography | 第97-99页 |
| ·Detection by mass spectrometric analysis, by direct injection method of analysis | 第99页 |
| ·Detection and confirmation by UPLC-MS | 第99-102页 |
| ·Color change patterns observed in the reactions | 第102-103页 |
| ·Summary | 第103-105页 |
| ·References | 第105-107页 |
| 4 Prebiotic hydrothermal synthesis of phospholipids and creation of cell like compartments | 第107-115页 |
| ·Introduction | 第107-109页 |
| ·Mechanism of formation of cellular vesicles | 第108-109页 |
| ·Prebiotic hydrothermal synthesis of lipids | 第109-111页 |
| ·Synthesis of ammonium palmitate | 第110页 |
| ·Preparation of mineral-clays mixture | 第110-111页 |
| ·Synthesis of phospholipids | 第111页 |
| ·Preparation self assembly structures | 第111-113页 |
| ·Dye encapsulation by vesicles | 第111-113页 |
| ·Summary | 第113-114页 |
| ·References | 第114-115页 |
| 5 Prebiotic Mineral Catalysis and Hydrothermal reactions of Formaldehyde | 第115-128页 |
| ·Introduction | 第115-119页 |
| ·Sources and Sinks of Prebiotic HCHO | 第115-116页 |
| ·Prebiotic chemistry of HCHO | 第116-117页 |
| ·HCHO interaction with minerals | 第117-119页 |
| ·Experimental | 第119-120页 |
| ·Mineral catalyzed hydrothermal reactions of HCHO | 第119-120页 |
| ·Scheme of the reaction | 第120-122页 |
| ·Characterization by GCMS | 第122-124页 |
| ·Summary | 第124-126页 |
| ·References | 第126-128页 |
| 6 Conclusion | 第128-131页 |
| Future Plans | 第131-133页 |
| Acknowledgements | 第133-135页 |
| Publications | 第135-136页 |
| Abstract in Chinese | 第136-142页 |
| Abstract in English | 第142-144页 |
